{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T20:01:30Z","timestamp":1791403290294,"version":"4.3.3"},"reference-count":36,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2022,3,28]],"date-time":"2022-03-28T00:00:00Z","timestamp":1648425600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100004312","name":"Eli Lilly and Company","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004312","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Dermatology"],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>The criteria used by physicians to assess alopecia areata severity and its associated burden from the patients' point of view are not well understood. We aimed to understand physician\u2010assessed determinants of disease severity, factors associated with severity, patient\u2013physician concordance, and patient\u2010reported burden by severity. Data were drawn from the Adelphi Alopecia Areata Disease Specific Programme\u2122, a point\u2010in\u2010time survey of dermatologists and their alopecia areata patients in real\u2010world practice in Japan conducted between January and March 2021. Patients were categorized into three groups by current disease severity according to physician subjective assessment: mild, moderate, or severe. Demographics, clinical characteristics, and outcomes were described within and compared between the three patient groups. Our study of 97 dermatologists and 587 patients found overall scalp hair loss was the most important factor considered by physicians in determining disease severity. More severe disease was associated with loss of eyebrow hair, eyelashes, and hair loss from other body areas. Agreement on disease severity between physicians and patients was moderate. From the patient perspective, greater severity of alopecia areata was associated with greater anxiety and depression, with lower work productivity and worse quality of life. Our study provides insights into which factors physicians use to determine alopecia areata severity, how physician and patient severity assessments compare, and the burden of alopecia areata on patients.<\/jats:p>","DOI":"10.1111\/1346-8138.16360","type":"journal-article","created":{"date-parts":[[2022,3,28]],"date-time":"2022-03-28T05:28:36Z","timestamp":1648445316000},"page":"575-583","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["Patient and physician perspectives on alopecia areata: A\n                    <scp>real\u2010world<\/scp>\n                    assessment of severity and burden in Japan"],"prefix":"10.1111","volume":"49","author":[{"given":"Emily","family":"Edson\u2010Heredia","sequence":"first","affiliation":[{"name":"Eli Lilly &amp; Company  Indianapolis Indiana USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshihiko","family":"Aranishi","sequence":"additional","affiliation":[{"name":"Eli Lilly Japan K.K.  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