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However, studies of pediatric SJS\/TEN are limited. To investigate the causes, clinical course, outcomes and complications of SJS and TEN in children. This retrospective study included 47 pediatric patients (aged\u2009&lt;\u200918\u2009years) with SJS, SJS\/TEN, or TEN treated at Chang Gung Memorial Hospital, Taiwan, between January 2009 and December 2019. ALDEN scores and serological tests were used to assess causes and SCORTEN scores were applied to evaluate disease severity. Forty\u2010seven patients, including 30 with SJS, 6 with SJS\/TEN, and 11 with TEN were included. Median age was 8\u2009years (range 1\u201317\u2009years); 51.1% were male. Thirty\u2010three cases (70.2%) were caused by drugs and infectious pathogens were suspected in 14 cases (29.8%). Oxcarbazepine (5\/47, 10.6%) and amoxicillin (5\/47, 10.6%) were the most often\u2010implicated drugs, and\n                    <jats:italic>Mycoplasma<\/jats:italic>\n                    infection (9\/47, 19.1%) was the predominant infectious cause. Only one TENS patient died (mortality rate 1\/47, 2.1%) due to septic shock with ARDS, acute renal failure and cardiopulmonary shock. Median hospital stay was 15.5 (3\u201342) days. Pulmonary involvement (2\/39, 5.1%), including pneumonia and ARDS, was noted in acute stage. Long\u2010term sequelae were ocular involvement (6\/39, 15.4%), nail dystrophy (4\/39, 10.3%) and post\u2010inflammatory hypo\u2010\/hyperpigmentation (3\/39, 7.7%). In the present study, pediatric patients with SJS, SJS\/TEN, or TEN have good outcomes with few long\u2010term complications and low mortality.\n                    <jats:italic>Mycoplasma<\/jats:italic>\n                    is the most common infectious cause in pediatric SJS\/TEN. Ocular discomfort, nail dystrophy and skin dyschromia are common long\u2010term sequelae requiring regular follow\u2010up.\n                  <\/jats:p>","DOI":"10.1111\/1346-8138.16476","type":"journal-article","created":{"date-parts":[[2022,6,18]],"date-time":"2022-06-18T02:04:57Z","timestamp":1655517897000},"page":"895-902","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Clinical features and outcomes in children with\n                    <scp>Stevens\u2013Johnson<\/scp>\n                    syndrome and toxic epidermal necrolysis"],"prefix":"10.1111","volume":"49","author":[{"given":"Min\u2010Hui","family":"Chi","sequence":"first","affiliation":[{"name":"Department of Dermatology, Drug Hypersensitivity Clinical and Research Center Chang Gung Memorial Hospital  Taipei,Linkuo and Keelung Taiwan"},{"name":"College of Medicine Chang Gung University  Taoyuan Taiwan"},{"name":"Institute of Molecular Medicine, College of Medicine National Taiwan University  Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen\u2010Hung","family":"Chung","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Drug Hypersensitivity Clinical and Research Center Chang Gung Memorial Hospital  Taipei,Linkuo and Keelung Taiwan"},{"name":"College of Medicine Chang Gung University  Taoyuan Taiwan"},{"name":"Chang Gung Immunology Consortium Chang Gung Memorial Hospital  Taiwan"},{"name":"Cancer Vaccine and Immune Cell Therapy Core Laboratory Chang Gung Memorial Hospital  Linkuo Taiwan"},{"name":"Immune\u2010Oncology Center of Excellence Chang Gung Memorial Hospital  Taoyuan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosaline Chung\u2010Yee","family":"Hui","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Drug Hypersensitivity Clinical and Research Center Chang Gung Memorial Hospital  Taipei,Linkuo and Keelung Taiwan"},{"name":"College of Medicine Chang Gung University  Taoyuan Taiwan"},{"name":"Chang Gung Immunology Consortium Chang Gung Memorial Hospital  Taiwan"},{"name":"Cancer Vaccine and Immune Cell Therapy Core Laboratory Chang Gung Memorial Hospital  Linkuo Taiwan"},{"name":"Immune\u2010Oncology Center of Excellence Chang Gung Memorial Hospital  Taoyuan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun\u2010Bing","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Drug Hypersensitivity Clinical and Research Center Chang Gung Memorial Hospital  Taipei,Linkuo and Keelung Taiwan"},{"name":"College of Medicine Chang Gung University  Taoyuan Taiwan"},{"name":"Chang Gung Immunology Consortium Chang Gung Memorial Hospital  Taiwan"},{"name":"Cancer Vaccine and Immune Cell Therapy Core Laboratory Chang Gung Memorial Hospital  Linkuo Taiwan"},{"name":"Immune\u2010Oncology Center of Excellence Chang Gung Memorial Hospital  Taoyuan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun\u2010Wei","family":"Lu","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Drug Hypersensitivity Clinical and Research Center Chang Gung Memorial Hospital  Taipei,Linkuo and Keelung Taiwan"},{"name":"College of Medicine Chang Gung University  Taoyuan Taiwan"},{"name":"Chang Gung Immunology Consortium Chang Gung Memorial Hospital  Taiwan"},{"name":"Cancer Vaccine and Immune Cell Therapy Core Laboratory Chang Gung Memorial Hospital  Linkuo Taiwan"},{"name":"Immune\u2010Oncology Center of Excellence Chang Gung Memorial Hospital  Taoyuan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tsu\u2010Man","family":"Chiu","sequence":"additional","affiliation":[{"name":"Department of Dermatology Changhua Christian Hospital  Changhua Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David Hui\u2010Kang","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Chang Gung Memorial Hospital  Taoyuan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chuang\u2010Wei","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Drug Hypersensitivity Clinical and Research Center Chang Gung Memorial Hospital  Taipei,Linkuo and Keelung Taiwan"},{"name":"College of Medicine Chang Gung University  Taoyuan Taiwan"},{"name":"Chang Gung Immunology Consortium Chang Gung Memorial Hospital  Taiwan"},{"name":"Cancer Vaccine and Immune Cell Therapy Core Laboratory Chang Gung Memorial Hospital  Linkuo Taiwan"},{"name":"Immune\u2010Oncology Center of Excellence Chang Gung Memorial Hospital  Taoyuan 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