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In early teens, although her cutaneous symptoms alleviated without any medications, she developed tremor and dysarthria. Neurological examination and brain imaging suggested demyelination disorders. The patient's cells indicated a reduced recovery of RNA synthesis, which was partially restored by the introduction of <jats:italic>CSB<\/jats:italic> (<jats:italic>Cockayne Syndrome B<\/jats:italic>)\u2010cDNA. In addition, her cells indicated a substantially reduced level of CSB protein. Despite the insidious progression of neurological symptoms, she gave birth to a child. Such mild cases of Cockayne syndrome may be misdiagnosed.<\/jats:p>","DOI":"10.1111\/1346-8138.16679","type":"journal-article","created":{"date-parts":[[2023,1,4]],"date-time":"2023-01-04T04:30:44Z","timestamp":1672806644000},"page":"541-545","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["A case of Cockayne syndrome with unusually mild clinical manifestations"],"prefix":"10.1111","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6541-5221","authenticated-orcid":false,"given":"Mariko","family":"Tsujimoto","sequence":"first","affiliation":[{"name":"Division of Dermatology, Department of Internal Related Kobe University Graduate School of Medicine  Kobe Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7632-8182","authenticated-orcid":false,"given":"Eiji","family":"Nakano","sequence":"additional","affiliation":[{"name":"Division of Dermatology, 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