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Biologics have revolutionized the treatment of adult psoriasis with higher efficacy and favorable safety profile. Recently, more studies have focused on the use of biologics in pediatric psoriasis, and several biologics have been approved for use therein. This review is divided into two sections: the first part focuses on real\u2010world studies on the use of biologics in pediatric psoriasis and the second part summarizes the findings of other clinical trials related to biologics in pediatric psoriasis. Case reports have been excluded from this review. Several biologics were used for treating pediatric psoriasis and the efficacy is encouraging. According to the studies included in this review, anti\u2010IL\u201012\/23 and anti\u2010IL\u201017A for treating pediatric psoriasis might have a better efficacy than anti\u2010TNF\u2010\u03b1, but more data are needed.<\/jats:p>","DOI":"10.1111\/1346-8138.16702","type":"journal-article","created":{"date-parts":[[2023,1,18]],"date-time":"2023-01-18T08:30:23Z","timestamp":1674030623000},"page":"415-421","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Biologics in pediatric psoriasis"],"prefix":"10.1111","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7905-9106","authenticated-orcid":false,"given":"Wen\u2010Ming","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Dermatology, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital Chinese Academy of Medical Science and Peking Union Medical College  Beijing 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