{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T12:43:38Z","timestamp":1763037818786,"version":"3.40.5"},"reference-count":14,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2023,1,5]],"date-time":"2023-01-05T00:00:00Z","timestamp":1672876800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Dermatology"],"published-print":{"date-parts":[[2023,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Autoimmune diseases triggered by coronavirus disease 2019 (COVID\u201019) mRNA vaccination have been emerging. Here, we report the case of a 27\u2010year\u2010old Japanese man with autoimmunity\u2010related neutrophilic dermatosis, occurring as an initial cutaneous manifestation of systemic lupus erythematosus with Sj\u00f6gren syndrome after the second dose of the Pfizer\/BioNTech COVID\u201019 vaccination. The patient presented with urticarial erythema and partially annular erythema on the trunk and extremities with severe pruritus. Histopathological analysis showed vacuolar degeneration at the dermo\u2010epidermal junction and interstitial neutrophil infiltration. We reviewed eight patients, including the aforementioned patient, with exacerbation or new\u2010onset of SLE after COVID\u201019 vaccination and found the patient had relatively mild symptoms, itchy annular erythema, and positive anti\u2010SS\u2010A\/SS\u2010B antibodies. COVID\u201019 mRNA vaccination can induce the production of type\u2010I interferon, which plays a crucial role in the pathogenesis of SLE and may cause autoimmunity\u2010related neutrophilic dermatosis in susceptible individuals. In the case that itchy annular erythema develops approximately 2\u2009weeks after the vaccination, the possibility of systemic or cutaneous lupus erythematosus should be considered. For an accurate diagnosis, dermatologists should obtain a recent vaccination history and perform complete antibody profiling and skin biopsy for patients presenting with annular or erythema multiforme\u2010like lesions.<\/jats:p>","DOI":"10.1111\/1346-8138.16718","type":"journal-article","created":{"date-parts":[[2023,1,6]],"date-time":"2023-01-06T07:32:25Z","timestamp":1672990345000},"page":"820-823","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Autoimmunity\u2010related neutrophilic dermatosis after coronavirus disease 2019 vaccination: A case report and literature review"],"prefix":"10.1111","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2966-1756","authenticated-orcid":false,"given":"Mari","family":"Kishibe","sequence":"first","affiliation":[{"name":"Department of Dermatology Asahikawa Medical University  Asahikawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katsuya","family":"Koike","sequence":"additional","affiliation":[{"name":"Department of Dermatology Nakashibetsu Town Hospital  Nakashibetsu Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3135-9254","authenticated-orcid":false,"given":"Kyoko","family":"Kanno","sequence":"additional","affiliation":[{"name":"Department of Dermatology Asahikawa Medical University  Asahikawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3104-102X","authenticated-orcid":false,"given":"Akemi","family":"Ishida\u2010Yamamoto","sequence":"additional","affiliation":[{"name":"Department of Dermatology Asahikawa Medical University  Asahikawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,1,5]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2020.617089"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000000346"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAP.0000000000000026"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0b013e3181943f5e"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/DAD.0b013e3182840f7f"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.15984"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2018.03.016"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11926-022-01063-9"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2013.00319"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/JLB.5COVR0621-320RR"},{"key":"e_1_2_6_12_1","first-page":"33","article-title":"The role of NETosis in systemic lupus erythematosus","volume":"1","author":"Salemme R","year":"2019","journal-title":"J Cell Immunol"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.18389"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdcr.2021.11.010"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40268-020-00320-5"}],"container-title":["The Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1346-8138.16718","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/1346-8138.16718","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1346-8138.16718","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,20]],"date-time":"2023-08-20T09:38:34Z","timestamp":1692524314000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1346-8138.16718"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1,5]]},"references-count":14,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2023,6]]}},"alternative-id":["10.1111\/1346-8138.16718"],"URL":"https:\/\/doi.org\/10.1111\/1346-8138.16718","archive":["Portico"],"relation":{},"ISSN":["0385-2407","1346-8138"],"issn-type":[{"type":"print","value":"0385-2407"},{"type":"electronic","value":"1346-8138"}],"subject":[],"published":{"date-parts":[[2023,1,5]]},"assertion":[{"value":"2022-09-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-12-27","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-01-05","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}