{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T00:20:06Z","timestamp":1747182006460,"version":"3.40.5"},"reference-count":14,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2023,2,28]],"date-time":"2023-02-28T00:00:00Z","timestamp":1677542400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Dermatology"],"published-print":{"date-parts":[[2023,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Squamous cell carcinoma (SCC) arises from a variety of premalignant conditions, including pyoderma. However, an accurate diagnosis of SCC is sometimes challenging due to indistinguishable inflammatory lesions. Here, we present a case of SCC arising from extensive pyoderma, which was successfully diagnosed by taking advantage of thallium\u2010201 scintigraphy. A 49\u2010year\u2010old man presented with an elevated tumor on his right buttock. Computed tomography (CT) and enhanced magnetic resonance imaging (MRI) identified the tumor, but many indistinguishable lesions were also found around the tumor. Histopathology revealed an atypical proliferation of keratinocytes with cancer pearls inside the tumor nests, while histopathology of nodules around the tumor revealed inflammatory tissues. Positron emission tomography CT (PET\/CT) revealed an accumulation of 2\u2010deoxy\u20102\u2010[<jats:sup>18<\/jats:sup>F]\u2010D\u2010glucose at the axillae and inguinal nodes, and at subcutaneous tissues in addition to the tumor. From the CT, enhanced MRI, and PET\/CT analyses it was impossible to differentiate many scattered subcutaneous nodules on the trunk from SCCs. However, thallium\u2010201 scintigraphy identified only the tumor and found no accumulation in other nodules. This finding suggests that thallium\u2010201 scintigraphy is useful for the diagnosis of SCC by excluding false\u2010positive signals detected by other imaging technologies.<\/jats:p>","DOI":"10.1111\/1346-8138.16756","type":"journal-article","created":{"date-parts":[[2023,3,5]],"date-time":"2023-03-05T08:00:52Z","timestamp":1678003252000},"page":"942-945","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["The potential value of thallium\u2010201 scintigraphy in the diagnosis of squamous cell carcinoma arising from extensive pyoderma"],"prefix":"10.1111","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1092-1159","authenticated-orcid":false,"given":"Takeshi","family":"Namiki","sequence":"first","affiliation":[{"name":"Department of Dermatology, Graduate School of Medical and Dental Sciences Tokyo Medical and Dental University  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Moe","family":"Makiguchi","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Graduate School of Medical and Dental Sciences Tokyo Medical and Dental University  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0153-1773","authenticated-orcid":false,"given":"Shogo","family":"Wada","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Graduate School of Medical and Dental Sciences Tokyo Medical and Dental University  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6537-2951","authenticated-orcid":false,"given":"Hind","family":"Al\u2010Busani","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Graduate School of Medical and Dental Sciences Tokyo Medical and Dental University  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Makiko","family":"Nishida","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Graduate School of Medical and Dental Sciences Tokyo Medical and Dental University  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tsukasa","family":"Ugajin","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Graduate School of Medical and Dental Sciences Tokyo Medical and Dental University  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9238-6067","authenticated-orcid":false,"given":"Keiko","family":"Miura","sequence":"additional","affiliation":[{"name":"Department of Pathology, Graduate School of Medical and Dental Sciences Tokyo Medical and Dental University  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kota","family":"Yokoyama","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Radiology, Graduate School of Medical and Dental Sciences Tokyo Medical and Dental University  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5398-0773","authenticated-orcid":false,"given":"Naoko","family":"Okiyama","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Graduate School of Medical and Dental Sciences Tokyo Medical and Dental University  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,2,28]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.2000.tb02268.x"},{"key":"e_1_2_5_3_1","first-page":"509","article-title":"Segmental analysis of Ti\u2010201 stress myocardial scintigraphy","volume":"18","author":"Lenaers A","year":"1977","journal-title":"J Nucl Med"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10741-017-9594-7"},{"key":"e_1_2_5_5_1","first-page":"3513","article-title":"Differentiating recurrent or residual nasopharyngeal carcinomas from post\u2010radiotherapy changes with 18\u2010fluoro\u20102\u2010deoxyglucose positron emission tomography and thallium\u2010201 single photon emission computed tomography in patients with indeterminate computed tomography findings","volume":"23","author":"Tsai MH","year":"2003","journal-title":"Anticaner Res"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1148\/rg.242025724"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/CCO.0000000000000430"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40336-021-00445-w"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cpet.2022.03.008"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cpet.2022.02.004"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm10245808"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.21377"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02985098"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12149-012-0608-1"},{"key":"e_1_2_5_15_1","first-page":"1837","article-title":"Comparison of thallium\u2010201 and F\u201018 FDG SPECT uptake in squamous cell carcinoma of the head and neck","volume":"15","author":"Mukherji SK","year":"1994","journal-title":"AJNR Am J Neuroradiol"}],"container-title":["The Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1346-8138.16756","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/1346-8138.16756","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1346-8138.16756","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,19]],"date-time":"2023-08-19T17:24:49Z","timestamp":1692465889000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1346-8138.16756"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,2,28]]},"references-count":14,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2023,7]]}},"alternative-id":["10.1111\/1346-8138.16756"],"URL":"https:\/\/doi.org\/10.1111\/1346-8138.16756","archive":["Portico"],"relation":{},"ISSN":["0385-2407","1346-8138"],"issn-type":[{"type":"print","value":"0385-2407"},{"type":"electronic","value":"1346-8138"}],"subject":[],"published":{"date-parts":[[2023,2,28]]},"assertion":[{"value":"2023-01-22","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-02-08","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-02-28","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}