{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T01:13:51Z","timestamp":1780535631671,"version":"3.54.1"},"reference-count":14,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2023,4,20]],"date-time":"2023-04-20T00:00:00Z","timestamp":1681948800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Dermatology"],"published-print":{"date-parts":[[2023,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Hyalohyphomycosis is a rare infection caused by a group of fungi that are devoid of pigments in their cell walls. As one of the main pathogens of hyalohyphomycosis, <jats:italic>Purpureocillium lilacinum<\/jats:italic> (former <jats:italic>Paecilomyces lilacinus<\/jats:italic>) is known for its intrinsic resistance to various antifungal agents. Here, we report three cases that coincide with a history of farming and all of them suffered from cutaneous hyalohyphomycosis caused by <jats:italic>P.\u2009lilacinum<\/jats:italic>. They shared a clinical presentation consisting of erythematous\u2010to\u2010violaceous painful plaques with overlying pustules on one of their forearms. Hyphae and fungal elements were highlighted by periodic acid Schiff or Gomori methenamine silver staining in their skin biopsies. Fungal cultures of their skin tissues yielded <jats:italic>P.\u2009lilacinum<\/jats:italic>, which was confirmed by both morphological and molecular characteristics<jats:italic>.<\/jats:italic> All patients responded well to oral terbinafine or itraconazole treatment. In this report, we also reviewed previously reported cases associated with either <jats:italic>P.\u2009lilacinum<\/jats:italic> or other <jats:italic>Paecilomyces<\/jats:italic> spp. infections in Taiwan.<\/jats:p>","DOI":"10.1111\/1346-8138.16806","type":"journal-article","created":{"date-parts":[[2023,4,21]],"date-time":"2023-04-21T06:30:20Z","timestamp":1682058620000},"page":"1088-1092","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Cutaneous infection caused by <i>Purpureocillium lilacinum<\/i>: Case reports and literature review of infections by <i>Purpureocillium<\/i> and <i>Paecilomyces<\/i> in Taiwan"],"prefix":"10.1111","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2647-2597","authenticated-orcid":false,"given":"Kun\u2010Lin","family":"Lu","sequence":"first","affiliation":[{"name":"Department of Dermatology Chang Gung Memorial Hospital  Linkou and Taipei Taiwan"},{"name":"College of Medicine Chang Gung University  Taoyuan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu\u2010Hsin","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Dermatology Chang Gung Memorial Hospital  Linkou and Taipei Taiwan"},{"name":"College of Medicine Chang Gung University  Taoyuan Taiwan"},{"name":"Department of Aesthetic Medicine Chang Gung Clinic  Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8057-771X","authenticated-orcid":false,"given":"Sze\u2010Wen","family":"Ting","sequence":"additional","affiliation":[{"name":"Department of Dermatology New Taipei City Municipal Tucheng Hospital  New Taipei City Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pei\u2010Lun","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Dermatology Chang Gung Memorial Hospital  Linkou and Taipei Taiwan"},{"name":"College of Medicine Chang Gung University  Taoyuan Taiwan"},{"name":"Research Laboratory of Medical Mycology Chang Gung Memorial Hospital, Linkou Branch  Taoyuan 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