{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T14:05:27Z","timestamp":1769695527306,"version":"3.49.0"},"reference-count":33,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2023,5,14]],"date-time":"2023-05-14T00:00:00Z","timestamp":1684022400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100002873","name":"Chulalongkorn University","doi-asserted-by":"publisher","award":["RA 62\/100"],"award-info":[{"award-number":["RA 62\/100"]}],"id":[{"id":"10.13039\/501100002873","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Dermatology"],"published-print":{"date-parts":[[2023,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:italic>Cutibacterium acnes<\/jats:italic> is associated with the pathogenesis of acne vulgaris (AV). The relationship between antibiotic\u2010resistant <jats:italic>C. acnes<\/jats:italic> and AV remains unclear. The authors aimed to determine the prevalence of antibiotic\u2010resistant <jats:italic>C. acnes<\/jats:italic> and investigate the association of acne severity with topical and systemic treatments in patients with acne. Samples were collected of inflammatory and noninflammatory acne, including closed and open comedones and erythematous papules\/pustules from the face of patients with mild to severe acne. The samples were cultured under anaerobic conditions for the isolation of <jats:italic>C. acnes<\/jats:italic>. Antibiotic susceptibility tests for erythromycin, tetracycline, doxycycline, clindamycin, and trimethoprim\/sulfamethoxazole were performed using the agar dilution method. From 153 patients, 143 viable <jats:italic>C. acnes<\/jats:italic> samples were isolated (93.5%). They were found resistant to trimethoprim\/sulfamethoxazole (143\/143, 100%), clindamycin (108\/143, 75.5%), erythromycin (105\/143, 73.4%), tetracycline (74\/143, 51.7%), and doxycycline (73\/143, 51.1%). There was no significant correlation between the prevalence of antibiotic resistance and acne severity. High\u2010level resistant <jats:italic>C. acnes<\/jats:italic> correlated with higher clinical severity of acne in patients taking doxycycline (<jats:italic>\u03c4<\/jats:italic><jats:sub><jats:italic>b<\/jats:italic><\/jats:sub>\u2009=\u20090.3). The present prevalence of antibiotic\u2010resistant <jats:italic>C. acnes<\/jats:italic> was high in Thailand. Antibiotic stewardship in AV treatment should be encouraged to prevent further antibiotic resistance crises.<\/jats:p>","DOI":"10.1111\/1346-8138.16823","type":"journal-article","created":{"date-parts":[[2023,5,15]],"date-time":"2023-05-15T07:00:00Z","timestamp":1684134000000},"page":"1008-1013","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["A cross\u2010sectional study examining the prevalence of antibiotic\u2010resistant <i>Cutibacterium acnes<\/i> isolated from patients with acne in Bangkok, Thailand"],"prefix":"10.1111","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9123-1183","authenticated-orcid":false,"given":"Peerada","family":"Sermswan","sequence":"first","affiliation":[{"name":"Faculty of Medicine King Mongkut's Institute of Technology Ladkrabang  Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rakwaree","family":"Sriharat","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Faculty of Medicine Chulalongkorn  Bangkok Thailand"},{"name":"Center of Excellence in Immunology and Immune\u2010Mediated Diseases, Department of Microbiology, Faculty of Medicine Chulalongkorn University  Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Supichcha","family":"Saithong","sequence":"additional","affiliation":[{"name":"Center of Excellence in Immunology and Immune\u2010Mediated Diseases, Department of Microbiology, Faculty of Medicine Chulalongkorn University  Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matchima","family":"Laowansiri","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Faculty of Medicine Chulalongkorn  Bangkok Thailand"},{"name":"Center of Excellence in Immunology and Immune\u2010Mediated Diseases, Department of Microbiology, Faculty of Medicine Chulalongkorn University  Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nutchaya","family":"Amornruk","sequence":"additional","affiliation":[{"name":"Center of Excellence in Immunology and Immune\u2010Mediated Diseases, Department of Microbiology, Faculty of Medicine Chulalongkorn University  Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Direkrit","family":"Chiewchengchol","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Faculty of Medicine Chulalongkorn  Bangkok Thailand"},{"name":"Center of Excellence in Immunology and Immune\u2010Mediated Diseases, Department of Microbiology, Faculty of Medicine Chulalongkorn University  Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nopadon","family":"Noppakun","sequence":"additional","affiliation":[{"name":"Division of Dermatology, Department of Medicine, Faculty of Medicine Chulalongkorn University and King Chulalongkorn Memorial Hospital, The Thai Red Cross Society  Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2628-0894","authenticated-orcid":false,"given":"Pravit","family":"Asawanonda","sequence":"additional","affiliation":[{"name":"Division of Dermatology, Department of Medicine, Faculty of Medicine Chulalongkorn University and King Chulalongkorn Memorial Hospital, The Thai Red Cross Society  Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tanittha","family":"Chatsuwan","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Faculty of Medicine Chulalongkorn  Bangkok Thailand"},{"name":"Center of Excellence in Antimicrobial Resistance and Stewardship, Faculty of Medicine Chulalongkorn University  Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8975-0523","authenticated-orcid":false,"given":"Chanat","family":"Kumtornrut","sequence":"additional","affiliation":[{"name":"Division of Dermatology, Department of Medicine, Faculty of Medicine Chulalongkorn University and King Chulalongkorn Memorial Hospital, The Thai Red Cross Society  Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,5,14]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.13462"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.12224"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2016.06.060"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2012.02.018"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(83)70005-8"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.2012.01626.x"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1099\/jmm.0.067611-0"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.2003.05067.x"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.16686"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1971.tb07195.x"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2010.04506.x"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2011.05371.x"},{"key":"e_1_2_9_14_1","volume-title":"CLSI M100\u2010ED30:2020 performance standards for antimicrobial susceptibility testing","author":"Institute CaLS","year":"2020"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2007.08087.x"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(15)00527-7"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clindermatol.2016.10.008"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1586\/14787210.2015.1040765"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/1346-8138.13149"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.12688\/f1000research.15659.1"},{"key":"e_1_2_9_21_1","first-page":"24","article-title":"In vitro study of antibiotic susceptibility of Propionibacterium acnes strains isolated from acne vulgaris patients","volume":"100","author":"Laochunsuwan A","year":"2017","journal-title":"J Med Assoc Thail"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.3390\/antibiotics10020137"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.15043"},{"key":"e_1_2_9_24_1","first-page":"773","article-title":"Differences of microbiomes found in non\u2010inflammatory and inflammatory lesions of acne vulgaris","volume":"13","author":"Jusuf NK","year":"2020","journal-title":"Clin Cosmet Investig Dermatol"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12895-020-00108-9"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1988.tb02437.x"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2015.12.037"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(85)70074-6"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2009.01.019"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(87)70200-X"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2003.618"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/1346-8138.12993"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.2147\/CCID.S311624"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2019.08.078"}],"container-title":["The Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1346-8138.16823","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,18]],"date-time":"2023-08-18T05:30:16Z","timestamp":1692336616000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1346-8138.16823"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5,14]]},"references-count":33,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2023,8]]}},"alternative-id":["10.1111\/1346-8138.16823"],"URL":"https:\/\/doi.org\/10.1111\/1346-8138.16823","archive":["Portico"],"relation":{},"ISSN":["0385-2407","1346-8138"],"issn-type":[{"value":"0385-2407","type":"print"},{"value":"1346-8138","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,5,14]]},"assertion":[{"value":"2023-03-20","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-04-23","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-05-14","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}