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The mechanisms by which dark brown pigments are generated in pigmented IKC are unclear. The authors report a case of pigmented IKC that had melanin pigments within the lining of the cyst wall and within the cyst. Focal infiltrates of lymphocytes were observed in the dermis, particularly beneath the cyst wall in areas with more melanocytes and intense melanin deposition. These pigmented parts faced bacterial colonies inside the cyst, which were identified to be <jats:italic>Corynebacterium<\/jats:italic> species in a bacterial flora analysis. The pathogenesis of pigmented IKC in relation to inflammation and bacterial flora is discussed.<\/jats:p>","DOI":"10.1111\/1346-8138.16871","type":"journal-article","created":{"date-parts":[[2023,6,27]],"date-time":"2023-06-27T08:09:11Z","timestamp":1687853351000},"page":"1488-1492","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Involvement of the genus <i>Corynebacterium<\/i> in the pathogenesis of pigmented intratarsal keratinous cyst"],"prefix":"10.1111","volume":"50","author":[{"given":"Miyuki","family":"Yoshikawa","sequence":"first","affiliation":[{"name":"Department of Dermatology Hirosaki University Graduate School of Medicine  Hirosaki Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2509-4483","authenticated-orcid":false,"given":"Daiki","family":"Rokunohe","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hirosaki University 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