{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T07:45:23Z","timestamp":1780472723790,"version":"3.54.1"},"reference-count":10,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Dermatology"],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Histiocytoid Sweet's syndrome (HSS) is a variant of Sweet's syndrome (SS) that clinically resembles SS but differs histologically by infiltrates, predominantly composed of immature cells of the myeloid lineage. Medications such as proteasome inhibitors have been reported to cause HSS but there has been little discussion on the underlying mechanism. Here we report two cases of HSS associated with a proteasome inhibitor. Both patients were on ixazomib for the treatment of multiple myeloma and presented with acute erythematous plaques on the upper half of the body. Pathological findings were consistent with HSS. Similarities between proteasome inhibitor\u2010induced HSS and Nakajo\u2010Nishimura syndrome, an inherited inflammatory disease, can be identified both clinically and histologically, suggesting a potential explanation of the mechanism behind proteasome inhibitor\u2010associated HSS.<\/jats:p>","DOI":"10.1111\/1346-8138.17201","type":"journal-article","created":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T14:55:05Z","timestamp":1711983305000},"page":"1355-1359","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Proteasome inhibitor\u2010associated histiocytoid Sweet's syndrome: Clinical and histological similarities to <scp>Nakajo\u2010Nishimura<\/scp> syndrome suggest a potential mechanism"],"prefix":"10.1111","volume":"51","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-7932-8266","authenticated-orcid":false,"given":"Ryang","family":"Cho","sequence":"first","affiliation":[{"name":"Department of Dermatology Kyoto University Graduate School of Medicine  Kyoto Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0831-1447","authenticated-orcid":false,"given":"Saeko","family":"Nakajima","sequence":"additional","affiliation":[{"name":"Department of Dermatology Kyoto University Graduate School of Medicine  Kyoto Japan"},{"name":"Department of Drug Discovery for Inflammatory Skin Diseases Kyoto University Graduate School of Medicine  Kyoto Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yo","family":"Kaku","sequence":"additional","affiliation":[{"name":"Department of Dermatology Kyoto University Graduate School of Medicine  Kyoto Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junko","family":"Tezuka","sequence":"additional","affiliation":[{"name":"Department of Dermatology Kyoto University Graduate School of Medicine  Kyoto Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masakazu","family":"Fujimoto","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Pathology Kyoto University Hospital  Kyoto Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9610-4952","authenticated-orcid":false,"given":"Naotomo","family":"Kambe","sequence":"additional","affiliation":[{"name":"Department of Dermatology Kyoto University Graduate School of Medicine  Kyoto Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0773-0554","authenticated-orcid":false,"given":"Kenji","family":"Kabashima","sequence":"additional","affiliation":[{"name":"Department of Dermatology Kyoto University Graduate School of Medicine  Kyoto Japan"},{"name":"A*STAR Skin Research Labs (A*SRL) Agency for Science, Technology and Research (A*STAR)  Singapore Singapore"},{"name":"Singapore Immunology Network (SIgN) Agency for Science, Technology and Research (A*STAR)  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,4]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.141.7.834"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2017.09.013"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/psp4.12815"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10555-017-9707-8"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.2177\/jsci.34.388"},{"key":"e_1_2_7_7_1","first-page":"1078","article-title":"Antinuclear antibodies in Nakajo\u2010Nishimura syndrome. A bridge with research on refractory autoimmune diseases","volume":"2","author":"Inaba Y","year":"2018","journal-title":"Trends Immunother"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/ijd.12695"},{"key":"e_1_2_7_9_1","article-title":"Interferon\u2010gamma coordinates CCL3\u2010mediated neutrophil recruitment in\u00a0vivo","volume":"14","author":"Bonville CA","year":"2009","journal-title":"BMC Immunol"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stemcr.2018.04.004"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2022.905960"}],"container-title":["The Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1346-8138.17201","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,3]],"date-time":"2024-10-03T07:23:00Z","timestamp":1727940180000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1346-8138.17201"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4]]},"references-count":10,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2024,10]]}},"alternative-id":["10.1111\/1346-8138.17201"],"URL":"https:\/\/doi.org\/10.1111\/1346-8138.17201","archive":["Portico"],"relation":{},"ISSN":["0385-2407","1346-8138"],"issn-type":[{"value":"0385-2407","type":"print"},{"value":"1346-8138","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,4]]},"assertion":[{"value":"2023-04-20","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-03-12","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-04-01","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}