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Here we report a case of radiation\u2010induced cSCC with a high level of tumor\u2010mutation burden that developed in a patient with MF who was successfully treated with pembrolizumab. The present case suggests that pembrolizumab might be an optimal therapy for radiation\u2010induced cSCC, even at advanced stages.<\/jats:p>","DOI":"10.1111\/1346-8138.17221","type":"journal-article","created":{"date-parts":[[2024,4,17]],"date-time":"2024-04-17T12:01:38Z","timestamp":1713355298000},"page":"1500-1503","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Radiation\u2010induced cutaneous squamous cell carcinoma showing a significant response to pembrolizumab: A case report"],"prefix":"10.1111","volume":"51","author":[{"given":"Manami","family":"Takahashi\u2010Watanabe","sequence":"first","affiliation":[{"name":"Department of Dermatology Tohoku University Graduate School of Medicine  Sendai 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