{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T18:27:34Z","timestamp":1761157654459,"version":"3.28.0"},"reference-count":12,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2024,8,19]],"date-time":"2024-08-19T00:00:00Z","timestamp":1724025600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Dermatology"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>An 86\u2010year\u2010old woman with residual left hemiplegia from a prior stroke, residing in a nursing facility, presented with swelling of the right side of her neck. Tuberculous lymphadenitis was diagnosed through polymerase chain reaction analysis and sputum culture, leading to treatment with isoniazid, rifampicin, and ethambutol. After 2\u2009months, an abscess and ulcer formed; analysis of the bacterial flora of the ulcer revealed a <jats:italic>Pseudomonas<\/jats:italic> infection. Treatment with a topical iodine\u2010containing ointment eradicated the <jats:italic>Pseudomonas<\/jats:italic> and led to increased diversity with the emergence of species from the Eukaryota and Archaea kingdoms. Subsequently, a loss of diversity occurred, ultimately resulting in a dominance of <jats:italic>Escherichia\u2010Shigella<\/jats:italic>. We suggest that the bacterial flora of early ulcers may be dominated by multidrug\u2010resistant <jats:italic>Pseudomonas<\/jats:italic>. <jats:italic>Escherichia\u2010Shigella<\/jats:italic> may emerge during the ulcer healing process. We, therefore, strongly encourage recognition of the fact that individuals with tuberculosis are immunocompromised and emphasize the critical importance of early intervention in such infections.<\/jats:p>","DOI":"10.1111\/1346-8138.17433","type":"journal-article","created":{"date-parts":[[2024,8,19]],"date-time":"2024-08-19T12:13:44Z","timestamp":1724069624000},"page":"1492-1495","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Changes in skin bacterial flora during the healing process of ulcer caused by self\u2010destruction of lymph nodes due to tuberculous lymphadenitis"],"prefix":"10.1111","volume":"51","author":[{"given":"Makoto","family":"Kondo","sequence":"first","affiliation":[{"name":"Department of Dermatology Mie University, Graduate School of Medicine  Tsu Mie Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daiki","family":"Goto","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Minamiise Municipal Hospital  Watarai Mie Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Koji","family":"Habe","sequence":"additional","affiliation":[{"name":"Department of Dermatology Mie University, Graduate School of Medicine  Tsu Mie Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naohisa","family":"Yamazoe","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Minamiise Municipal Hospital  Watarai Mie Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keiichi","family":"Yamanaka","sequence":"additional","affiliation":[{"name":"Department of Dermatology Mie University, Graduate School of Medicine  Tsu Mie Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,8,19]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/1346-8138.13072"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2012.347"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jid.2018.04.026"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1159\/000516354"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.16081"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro.2017.157"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1128\/am.28.6.987-991.1974"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-1605(99)00151-8"},{"key":"e_1_2_10_10_1","first-page":"Chapter\u00a027","volume-title":"Medical Microbiology","author":"Iglewski BH","year":"1996"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-443-06839-3.00219-8"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1086\/514550"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2020.00101"}],"container-title":["The Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1346-8138.17433","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,2]],"date-time":"2024-11-02T04:29:26Z","timestamp":1730521766000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1346-8138.17433"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8,19]]},"references-count":12,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2024,11]]}},"alternative-id":["10.1111\/1346-8138.17433"],"URL":"https:\/\/doi.org\/10.1111\/1346-8138.17433","archive":["Portico"],"relation":{},"ISSN":["0385-2407","1346-8138"],"issn-type":[{"type":"print","value":"0385-2407"},{"type":"electronic","value":"1346-8138"}],"subject":[],"published":{"date-parts":[[2024,8,19]]},"assertion":[{"value":"2024-02-27","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-08-02","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-08-19","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}