{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T14:47:15Z","timestamp":1787237235588,"version":"build-2736575974"},"reference-count":5,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,10,20]],"date-time":"2024-10-20T00:00:00Z","timestamp":1729382400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2024,10,20]],"date-time":"2024-10-20T00:00:00Z","timestamp":1729382400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Dermatology"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Psoriasis is a chronic inflammatory skin disease characterized by keratinocyte hyperproliferation and immune cell infiltration. Various therapies have been discovered for psoriasis, including topical treatments, phototherapy, conventional systemic agents such as methotrexate, retinoids and ciclosporine, as well as biologics. Janus kinase\/signal transducer and activator of transcription (JAK\/STAT) pathway inhibitors targeting Tumor Necrosis Factor alpha (TNF\u2010\u03b1), interleukin (IL)\u201023 and IL\u201017 can be effective in psoriasis. Ruxolitinib is a US Food and Drug Administration\u2010approved first\u2010generation Janus kinase inhibitor for polycythemia vera, myelofibrosis, and acute graft\u2010versus\u2010host disease. Ruxolitinib cream has been investigated in various dermatologic diseases, including atopic dermatitis, vitiligo, psoriasis, and alopecia areata. However, there is limited data on the efficacy of oral ruxolitinib in patients with psoriasis vulgaris. Here, we report a patient diagnosed with myelofibrosis coexisting with psoriasis vulgaris, successfully treated with oral ruxolitinib.<\/jats:p>","DOI":"10.1111\/1346-8138.17510","type":"journal-article","created":{"date-parts":[[2024,10,21]],"date-time":"2024-10-21T02:03:58Z","timestamp":1729476238000},"page":"179-182","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Oral administration of ruxolitinib in psoriasis vulgaris: A case report of plaque psoriasis accompanied by myelofibrosis secondary to polisitemia vera successfully treated with oral ruxolitinib"],"prefix":"10.1111","volume":"52","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2847-9127","authenticated-orcid":false,"given":"Tubanur","family":"\u00c7etinarslan","sequence":"first","affiliation":[{"name":"Department of Dermatology and Venereology Manisa Celal Bayar University  Manisa Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u0130smet","family":"Aydo\u011fdu","sequence":"additional","affiliation":[{"name":"Department of Hematology Manisa Celal Bayar University  Manisa Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7720-5491","authenticated-orcid":false,"given":"Aylin T\u00fcrel","family":"Ermertcan","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology Manisa Celal Bayar University  Manisa Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,10,20]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.3390\/pharmaceutics13071044"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1080\/09546634.2020.1773385"},{"key":"e_1_2_7_4_1","unstructured":"UphamB.FDA approves new vitiligo treatment Ruxolitinib (Opzelura): Everyday health.2022.https:\/\/www.everydayhealth.com\/vitiligo\/fda\u2010approves\u2010new\u2010vitiligo\u2010treatment\u2010ruxolitinib\u2010opzelura\/"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2011.12.018"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers15205085"}],"container-title":["The Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1346-8138.17510","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/1346-8138.17510","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1346-8138.17510","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,15]],"date-time":"2026-03-15T13:45:07Z","timestamp":1773582307000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1346-8138.17510"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10,20]]},"references-count":5,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1]]}},"alternative-id":["10.1111\/1346-8138.17510"],"URL":"https:\/\/doi.org\/10.1111\/1346-8138.17510","archive":["Portico"],"relation":{},"ISSN":["0385-2407","1346-8138"],"issn-type":[{"value":"0385-2407","type":"print"},{"value":"1346-8138","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,10,20]]},"assertion":[{"value":"2024-07-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-10-03","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-10-20","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}