{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,15]],"date-time":"2026-03-15T15:28:01Z","timestamp":1773588481305,"version":"3.50.1"},"reference-count":20,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,11,18]],"date-time":"2024-11-18T00:00:00Z","timestamp":1731888000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2024,11,18]],"date-time":"2024-11-18T00:00:00Z","timestamp":1731888000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Dermatology"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Non\u2010IgA vasculitis is a rare disease that belongs to the group of small\u2010vessel vasculitides. Due to nomenclature and classification changes introduced in 2018, there are few published data under this name. The aim of this study is to characterize non\u2010IgA vasculitis as an independent vasculitis entity in terms of demographic, clinical, and treatment\u2010related features. A retrospective data analysis of patients with biopsy\u2010confirmed non\u2010IgA vasculitis treated at the Department of Dermatology at the University Medical Center Hamburg\u2010Eppendorf between January 1, 2018, and December 31, 2022, was performed. A total of 28 patients with non\u2010IgA vasculitis were included; 53.6% (15\/28) were women and 42.9% (12\/28) were older than 71\u2009years. Previous infection as a possible triggering factor was found in 42.6% (12\/28) of the cases. Palpable purpura was the most common skin finding (78.6%, 22\/28) and 28.6% patients (8\/28) had skin lesions above the waist. On direct immunofluorescence, C3 (89.3%, 25\/28) was the most frequent deposition, followed by fibrinogen (71.4%, 20\/28) and IgM (53.6%, 15\/28). Hospitalization was required in 85.7% (24\/28), with a mean hospital stay of 9.4\u2009\u00b1\u20094.1\u2009days. No fatal courses were reported. This study is the first characterization of non\u2010IgA vasculitis based on patient cases from Germany and contributes to a better understanding of non\u2010IgA vasculitis as an independent entity. Non\u2010IgA vasculitis primarily affects older patients of both sexes, with most cases having an identifiable trigger. Our results indicate that cutaneous manifestations often extend beyond the lower legs. Treatment is usually required in the inpatient setting and requires a longer stay than other dermatological conditions. With proper treatment, the disease is not expected to be fatal.<\/jats:p>","DOI":"10.1111\/1346-8138.17545","type":"journal-article","created":{"date-parts":[[2024,11,18]],"date-time":"2024-11-18T08:34:16Z","timestamp":1731918856000},"page":"43-49","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Characterization of non\u2010\n                    <scp>IgA<\/scp>\n                    vasculitis: Demographic, clinical, and treatment\u2010related features in a retrospective analysis of 28 biopsy\u2010confirmed cases from a German university hospital"],"prefix":"10.1111","volume":"52","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-5579-4337","authenticated-orcid":false,"given":"Inga","family":"Hansen\u2010Abeck","sequence":"first","affiliation":[{"name":"Department of Dermatology and Venereology University Medical Center Hamburg\u2010Eppendorf  Hamburg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandra","family":"R\u00fcnger","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology University Medical Center Hamburg\u2010Eppendorf  Hamburg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lisa","family":"Piepke","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology University Medical Center Hamburg\u2010Eppendorf  Hamburg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2073-3909","authenticated-orcid":false,"given":"Julian","family":"K\u00f6tt","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology University Medical Center Hamburg\u2010Eppendorf  Hamburg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Giordano\u2010Rosenbaum","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology University Medical Center Hamburg\u2010Eppendorf  Hamburg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne","family":"Menz","sequence":"additional","affiliation":[{"name":"Institute of Pathology University Medical Center Hamburg\u2010Eppendorf  Hamburg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Finn","family":"Abeck","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology University Medical Center Hamburg\u2010Eppendorf  Hamburg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefan W.","family":"Schneider","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology University Medical Center Hamburg\u2010Eppendorf  Hamburg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,11,18]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.40375"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keu295"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00108-019-0641-4"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/ddg.13703"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00108-019-0642-3"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.2165\/00128071-200809020-00001"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.2147\/PHMT.S379862"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1529-8019.2012.01535.x"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11739-021-02688-x"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11926-021-01012-y"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2020.04.060"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1159\/000521288"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keab312"},{"issue":"5","key":"e_1_2_9_15_1","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1111\/ddg.14620","article-title":"Inpatient care for skin diseases in Germany: multi\u2010source analysis on the current and future health care needs","volume":"19","author":"Augustin M","year":"2021","journal-title":"J Dtsch Dermatol Ges"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.134.3.309"},{"key":"e_1_2_9_17_1","first-page":"531","article-title":"Cutaneous leukocytoclastic vasculitis: the yield of direct immunofluorescence study","volume":"87","author":"Kulthanan K","year":"2004","journal-title":"J Med Assoc Thail"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.4103\/0971-5916.93432"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00296-020-04631-3"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00108-021-01181-z"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1155\/2022\/8110940"}],"container-title":["The Journal of 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