{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,8]],"date-time":"2025-04-08T04:25:57Z","timestamp":1744086357966,"version":"3.40.3"},"reference-count":11,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,1,8]],"date-time":"2025-01-08T00:00:00Z","timestamp":1736294400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Dermatology"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Trichogerminoma (TG) is a rare, benign, cutaneous adnexal tumor originating from the hair germ epithelium. It typically presents as an asymptomatic, slowly enlarging nodule predominantly on the head, face, or trunk. Despite its benign nature, precise diagnosis is crucial because of its potential to become malignant. There has been no previous report on the dermoscopic findings of TG. In this study, we reviewed the dermoscopic findings of two cases in detail and contrasted them with the pathological findings. In the first case, an 80\u2010year\u2010old male presented with a forehead nodule that was initially suspected to be basal cell carcinoma (BCC). Dermoscopic examination revealed arborizing vessels, milia\u2010like cysts, and comedo\u2010like openings. Histological examination supported a diagnosis of TG, showing basaloid cell nests with peripheral palisading and pathognomonic \u201ccell balls.\u201d The second case involved a 50\u2010year\u2010old female with a nodular lesion on her scalp. Dermoscopy showed arborizing vessels, milia\u2010like cysts, and blue\u2010gray ovoid nests. Based on the presence of \u201ccell balls\u201d observed in histopathological examination, this case was also diagnosed as TG. This report is seminal in documenting the specific dermoscopic patterns associated with TG, notably the presence of arborizing vessels in conjunction with features indicative of adnexal differentiation, such as milia\u2010like cysts and comedo\u2010like openings. Although differentiating TG from other follicular tumors such as BCC and trichoblastoma based solely on dermoscopy is challenging, these features suggest follicular differentiation in TG. This report contributes uniquely to the existing data on TG, enhancing our understanding of this rare tumor and how to diagnose it.<\/jats:p>","DOI":"10.1111\/1346-8138.17610","type":"journal-article","created":{"date-parts":[[2025,1,9]],"date-time":"2025-01-09T07:58:33Z","timestamp":1736409513000},"page":"730-734","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Dermoscopic findings in two cases of trichogerminoma"],"prefix":"10.1111","volume":"52","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-7031-827X","authenticated-orcid":false,"given":"George","family":"Miura","sequence":"first","affiliation":[{"name":"Department of Dermatology, Faculty of Medicine, Graduate School of Medicine Hokkaido University  Sapporo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9332-4773","authenticated-orcid":false,"given":"Takuya","family":"Maeda","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Faculty of Medicine, Graduate School of Medicine Hokkaido University  Sapporo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3489-5418","authenticated-orcid":false,"given":"Hideyuki","family":"Ujiie","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Faculty of Medicine, Graduate School of Medicine Hokkaido University  Sapporo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,1,8]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0560.1992.tb00606.x"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.5021\/ad.2010.22.4.431"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/1346-8138.13657"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/DAD.0b013e31818ffcc3"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2559.2005.01955.x"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/DAD.0000000000000921"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.32074\/1591-951X-137"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1159\/000066427"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1186\/1746-1596-8-210"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ad.2016.04.013"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers14163964"}],"container-title":["The Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1346-8138.17610","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,7]],"date-time":"2025-04-07T21:52:42Z","timestamp":1744062762000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1346-8138.17610"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,8]]},"references-count":11,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,4]]}},"alternative-id":["10.1111\/1346-8138.17610"],"URL":"https:\/\/doi.org\/10.1111\/1346-8138.17610","archive":["Portico"],"relation":{},"ISSN":["0385-2407","1346-8138"],"issn-type":[{"type":"print","value":"0385-2407"},{"type":"electronic","value":"1346-8138"}],"subject":[],"published":{"date-parts":[[2025,1,8]]},"assertion":[{"value":"2024-11-11","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-12-19","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-01-08","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}