{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T16:46:53Z","timestamp":1776703613278,"version":"3.51.2"},"reference-count":10,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2025,5,19]],"date-time":"2025-05-19T00:00:00Z","timestamp":1747612800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Dermatology"],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>Antinuclear matrix protein 2 (NXP\u20102) antibodies are dermatomyositis\u2010specific antibodies that target NXP\u20102 involved in transcriptional regulation. However, their clinical significance and relationship with disease activity remain unclear. We performed a longitudinal examination on serum samples from three patients with dermatomyositis who tested positive for anti\u2010NXP\u20102 antibodies. These serum samples were analyzed alongside clinical parameters, including disease activity, muscle enzyme levels, and treatment response. The levels of anti\u2010NXP\u20102 antibodies and serum creatine kinase decreased with symptom improvement in all the cases. Anti\u2010NXP\u20102 antibody levels showed a correlation with disease activity, suggesting their potential role as a marker of disease activity.<\/jats:p>","DOI":"10.1111\/1346-8138.17767","type":"journal-article","created":{"date-parts":[[2025,5,19]],"date-time":"2025-05-19T08:45:54Z","timestamp":1747644354000},"page":"1197-1200","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Clinical Significance of Serum Levels of Anti\u2010Nuclear Matrix Protein 2 Antibodies in Patients With Dermatomyositis"],"prefix":"10.1111","volume":"52","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-7579-6739","authenticated-orcid":false,"given":"Satoko","family":"Yuasa","sequence":"first","affiliation":[{"name":"Department of Dermatology Fujita Health University School of Medicine  Toyoake Aichi Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7846-2729","authenticated-orcid":false,"given":"Yohei","family":"Iwata","sequence":"additional","affiliation":[{"name":"Department of Dermatology Fujita Health University School of Medicine  Toyoake Aichi Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4647-030X","authenticated-orcid":false,"given":"Kenta","family":"Saito","sequence":"additional","affiliation":[{"name":"Department of Dermatology Fujita Health University School of Medicine  Toyoake Aichi Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2329-8375","authenticated-orcid":false,"given":"Yoshinao","family":"Muro","sequence":"additional","affiliation":[{"name":"Department of Dermatology Nagoya University Graduate School of Medicine  Nagoya Aichi Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazumitsu","family":"Sugiura","sequence":"additional","affiliation":[{"name":"Department of Dermatology Fujita Health University School of Medicine  Toyoake Aichi Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,5,19]]},"reference":[{"key":"e_1_2_6_2_1","first-page":"139","article-title":"Clinical and Serological Characterization of the Anti\u2010MJ Antibody in Childhood Myositis","volume":"40","author":"Oddis C.","year":"1997","journal-title":"Arthritis and Rheumatism"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/kem359"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.3899\/jrheum.090461"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keu259"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.38093"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2011-200697"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/kes033"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2009.09521.x"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.40491"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keab518"}],"container-title":["The Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1346-8138.17767","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,4]],"date-time":"2025-07-04T04:20:47Z","timestamp":1751602847000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1346-8138.17767"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,19]]},"references-count":10,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2025,7]]}},"alternative-id":["10.1111\/1346-8138.17767"],"URL":"https:\/\/doi.org\/10.1111\/1346-8138.17767","archive":["Portico"],"relation":{},"ISSN":["0385-2407","1346-8138"],"issn-type":[{"value":"0385-2407","type":"print"},{"value":"1346-8138","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,5,19]]},"assertion":[{"value":"2024-08-13","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-04-19","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-05-19","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}