{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T09:16:03Z","timestamp":1788513363703,"version":"build-2803163510"},"reference-count":15,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2025,7,12]],"date-time":"2025-07-12T00:00:00Z","timestamp":1752278400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,7,12]],"date-time":"2025-07-12T00:00:00Z","timestamp":1752278400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Dermatology"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Brain metastasis from cutaneous angiosarcoma of the scalp is rare, and the characteristics and optimal treatment remain poorly understood. Herein, we report three cases of brain metastasis originating from cAS of the scalp. Case 1: An 81\u2010year\u2010old male developed lung metastasis 2.5\u2009years after initial diagnosis, followed by brain metastasis 1\u2009year later. He passed away 1\u2009month after the detection of brain metastasis. Case 2: A 66\u2010year\u2010old male presented with lung and cervical lymph node metastases at the time of initial diagnosis. Brain metastasis was identified 5\u2009months later after the onset of dizziness, and he passed away 2\u2009months thereafter. Case 3: A 68\u2010year\u2010old male developed lung metastasis 7\u2009months after initial diagnosis. Brain metastasis was detected 1\u2009month later via computed tomography (CT). Palliative radiation therapy (30\u2009Gy) led to a reduction in the size of the metastatic brain lesion; however, he passed away 2\u2009months later. In each case, plain CT scans showed multiple high\u2010density areas. The period from brain metastasis detection to death was uniformly short, within 2\u2009months. These findings suggest that brain metastasis in cutaneous angiosarcoma of the scalp is associated with a poor prognosis.<\/jats:p>","DOI":"10.1111\/1346-8138.17858","type":"journal-article","created":{"date-parts":[[2025,7,12]],"date-time":"2025-07-12T08:04:45Z","timestamp":1752307485000},"page":"1456-1460","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Brain Metastasis From Angiosarcoma of the Scalp: Report of Three Cases"],"prefix":"10.1111","volume":"52","author":[{"given":"Mami","family":"Kudo","sequence":"first","affiliation":[{"name":"Department of Dermatology Graduate School of Medicine, University of the Ryukyus  Ginowan Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Riku","family":"Shirato","sequence":"additional","affiliation":[{"name":"Department of Dermatology Graduate School of Medicine, University of the Ryukyus  Ginowan Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2196-7600","authenticated-orcid":false,"given":"Teruki","family":"Yanagi","sequence":"additional","affiliation":[{"name":"Department of Dermatology Graduate School of Medicine, University of the Ryukyus  Ginowan Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wataru","family":"Yamagata","sequence":"additional","affiliation":[{"name":"Department of Radiology Graduate School of Medicine, University of the Ryukyus  Ginowan Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akira","family":"Yogi","sequence":"additional","affiliation":[{"name":"Department of Radiology Graduate School of Medicine, University of the Ryukyus  Ginowan Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aoi","family":"Ohira","sequence":"additional","affiliation":[{"name":"Department of Dermatology Graduate School of Medicine, University of the Ryukyus  Ginowan Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ririko","family":"Iwamoto","sequence":"additional","affiliation":[{"name":"Department of Dermatology Graduate School of Medicine, University of the Ryukyus  Ginowan Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenzo","family":"Takahashi","sequence":"additional","affiliation":[{"name":"Department of Dermatology Graduate School of Medicine, University of the Ryukyus  Ginowan Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,7,12]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/CCO.0000000000000427"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/cas.16453"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/1346-8138.16273"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2018.02.246"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00432-016-2151-2"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-022-08362-2"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.16714"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.3892\/ol.2015.2919"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.5070\/D32310036995"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10143-019-01127-y"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/pcmr.12538"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2020.05.094"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoncol.2015.1206"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI139080"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jix424"}],"container-title":["The Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1346-8138.17858","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/1346-8138.17858","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1346-8138.17858","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T08:42:08Z","timestamp":1788511328000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1346-8138.17858"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,12]]},"references-count":15,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2025,9]]}},"alternative-id":["10.1111\/1346-8138.17858"],"URL":"https:\/\/doi.org\/10.1111\/1346-8138.17858","archive":["Portico"],"relation":{},"ISSN":["0385-2407","1346-8138"],"issn-type":[{"value":"0385-2407","type":"print"},{"value":"1346-8138","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7,12]]},"assertion":[{"value":"2025-02-24","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-07-04","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-07-12","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}