{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T16:29:50Z","timestamp":1773419390884,"version":"3.50.1"},"reference-count":15,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T00:00:00Z","timestamp":1761004800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T00:00:00Z","timestamp":1761004800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Dermatology"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Patients with cutaneous lupus erythematosus (CLE) are highly susceptible to nonmelanoma skin cancers, including cutaneous squamous cell carcinoma (SCC). Despite the well\u2010established involvement of plasmacytoid dendritic cells (pDCs) in CLE development, the exact role of pDCs in the pathogenesis of CLE\u2010related SCC remains unclear. This report presents a case of SCC arising from a subacute cutaneous lupus erythematosus (SCLE) lesion. Histopathological examination revealed a notable decrease in CD123\n                    <jats:sup>+<\/jats:sup>\n                    pDCs in the SCC lesion compared with that in the SCLE lesion in the same patient. pDCs may exert cytotoxic effects against cancer cells; thus, the absence of pDCs in the microenvironment of cutaneous SCC may facilitate immune evasion by cancer cells, thereby promoting tumor progression. These findings indicate the complex relationship between pDCs and cutaneous SCC development in patients with CLE. Future studies should clarify the role of pDCs in tumor surveillance and progression.\n                  <\/jats:p>","DOI":"10.1111\/1346-8138.70017","type":"journal-article","created":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T16:03:29Z","timestamp":1761062609000},"page":"126-130","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Decreased Plasmacytoid Dendritic Cells in Cutaneous Squamous Cell Carcinoma Arising From Subacute Cutaneous Lupus Erythematosus: A Case Report"],"prefix":"10.1111","volume":"53","author":[{"given":"Yao\u2010Yu","family":"Lu","sequence":"first","affiliation":[{"name":"Department of Dermatology Taipei Medical University\u2010Shuang Ho Hospital  New Taipei City Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu\u2010Cheng","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Dermatology Taipei Municipal Wan Fang Hospital  Taipei Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yun\u2010Wen","family":"Chiu","sequence":"additional","affiliation":[{"name":"Department of Dermatology Taipei Medical University\u2010Shuang Ho Hospital  New Taipei City Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7198-7234","authenticated-orcid":false,"given":"Shiou\u2010Fu","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Pathology Taipei Medical University\u2010Shuang Ho Hospital  New Taipei City Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2095-7064","authenticated-orcid":false,"given":"Yi\u2010Hsien","family":"Shih","sequence":"additional","affiliation":[{"name":"Department of Dermatology Taipei Medical University\u2010Shuang Ho Hospital  New Taipei City Taiwan"},{"name":"Department of Dermatology, School of Medicine, College of Medicine Taipei Medical University  Taipei Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,10,21]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2014.316"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365\u20102133.2011.10773.x"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1177\/0961203321990106"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdermsci.2016.05.008"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.imbio.2009.06.013"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/SMJ.0b013e3181c98ba9"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2011.09.033"},{"issue":"6","key":"e_1_2_8_9_1","first-page":"946","article-title":"The Influence of Immunosuppressants on the Non\u2010Melanoma Skin Cancer Among Patients With Systemic Lupus Erythematosus and Primary Sj\u00f6gren's Syndrome: A Nationwide Retrospective Case\u2010Control Study in Taiwan","volume":"37","author":"Tseng H. 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