{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T06:15:00Z","timestamp":1788156900043,"version":"build-2803163510"},"reference-count":46,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T00:00:00Z","timestamp":1787270400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T00:00:00Z","timestamp":1787270400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Dermatology"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>This study aimed to compare depressive symptoms, anxiety symptoms, and health\u2010related quality of life between children with molluscum contagiosum and healthy controls and to examine whether lesion number and anatomical localization were associated with these outcomes. This prospectively conducted cross\u2010sectional study included 72 children with molluscum contagiosum and 80 age\u2010 and sex\u2010matched healthy controls aged 6\u201312\u2009years. Depressive symptoms, anxiety symptoms, and health\u2010related quality of life were assessed using validated pediatric instruments. Psychological outcomes were also compared according to lesion number and anatomical localization. Children with molluscum contagiosum had significantly higher depression and anxiety scores and significantly lower total quality\u2010of\u2010life scores than healthy controls. Depression and anxiety scores differed significantly according to lesion localization. Children with lesions involving highly visible areas, including the face, periocular region, lips, and hands, had higher depression and anxiety scores than those with lesions on the trunk and legs. Lesion number was not significantly associated with depression, anxiety, or quality\u2010of\u2010life scores. Female sex was independently associated with approximately twofold higher odds of an elevated anxiety score. Children with molluscum contagiosum may experience greater depressive and anxiety symptoms and poorer health\u2010related quality of life than healthy peers. Psychological burden appears to be more closely related to lesion visibility and anatomical localization than to lesion number alone. These findings support consideration of psychological screening, particularly in children with highly visible lesions, and highlight the relevance of a broader psychodermatological approach.<\/jats:p>","DOI":"10.1111\/1346-8138.70443","type":"journal-article","created":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T07:41:34Z","timestamp":1787298094000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The Impact of Molluscum Contagiosum on Depression, Anxiety and Quality of Life in Children"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7909-9944","authenticated-orcid":false,"given":"Abdulbaki","family":"Artik","sequence":"first","affiliation":[{"name":"Child and Adolescent Psychiatry Department, Gulhane Training and Research Hospital University of Health Sciences  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3074-5989","authenticated-orcid":false,"given":"Hatice","family":"Atas","sequence":"additional","affiliation":[{"name":"Dermatology and Venereology Department Etlik City Hospital  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2612-8080","authenticated-orcid":false,"given":"Tugcan","family":"Yuksek","sequence":"additional","affiliation":[{"name":"Dermatology and Venereology Department Etlik City Hospital  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6758-6208","authenticated-orcid":false,"given":"Erman","family":"Atas","sequence":"additional","affiliation":[{"name":"General Pediatric Department, Gulhane Training and Research Hospital University of Health Sciences  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1243-8731","authenticated-orcid":false,"given":"Bahar Oztelcan","family":"Gunduz","sequence":"additional","affiliation":[{"name":"General Pediatric Department, Gulhane Training and Research Hospital University of Health Sciences  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7588-3288","authenticated-orcid":false,"given":"Huseyin Ilgin","family":"Bal","sequence":"additional","affiliation":[{"name":"General Pediatric Department Etlik City Hospital  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7310-8635","authenticated-orcid":false,"given":"Selda Pelin","family":"Kartal","sequence":"additional","affiliation":[{"name":"Dermatology and Venereology Department Etlik City Hospital  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-0143-3890","authenticated-orcid":false,"given":"Halenur","family":"Teke","sequence":"additional","affiliation":[{"name":"Child and Adolescent Psychiatry Department, Gulhane Training and Research Hospital University of Health Sciences  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8964-9513","authenticated-orcid":false,"given":"Burak","family":"A\u00e7\u0131kel","sequence":"additional","affiliation":[{"name":"Child and Adolescent Psychiatry Department Ankara University Faculty of Medicine  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6906-573X","authenticated-orcid":false,"given":"Mustafa S\u0131rr\u0131","family":"Kotano\u011flu","sequence":"additional","affiliation":[{"name":"Ankara Etlik City Hospital  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-2550-6992","authenticated-orcid":false,"given":"Mehri","family":"Durak","sequence":"additional","affiliation":[{"name":"Child and Adolescent Psychiatry Department, Gulhane Training and Research Hospital University of Health Sciences  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,21]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1440\u20100960.1999.00327.x"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.5826\/dpc.0603a15"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/fampra\/cmt075"},{"issue":"8","key":"e_1_2_12_5_1","first-page":"S4","article-title":"Molluscum Contagiosum: Epidemiology, Considerations, Treatment Options, and Therapeutic Gaps","volume":"16","author":"Hebert A. A.","year":"2023","journal-title":"Journal of Clinical and Aesthetic Dermatology"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0738\u2010081x(01)00233\u20104"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/9781119142812.ch48"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2022.2721"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02737869"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.4088\/pcc.v09n0306"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2008.417"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1017\/CBO9780511544170.004"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/ddg.14328"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.4103\/idoj.idoj_458_24"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1177\/13591053251383649"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.4274\/tjd.galenos.2025.19870"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.14744\/nci.2025.26928"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.5505\/ejm.2021.52280"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.4274\/haseki.galenos.2021.7183"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/aphw.70097"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.17110"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.1080\/13548506.2026.2653105"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.1093\/ced\/llaf471"},{"key":"e_1_2_12_24_1","doi-asserted-by":"publisher","DOI":"10.4103\/0974\u20107753.189005"},{"key":"e_1_2_12_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/ddg.14234"},{"key":"e_1_2_12_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473\u20103099(14)71053\u20109"},{"issue":"2","key":"e_1_2_12_27_1","first-page":"132","article-title":"\u00c7ocuklar i\u00e7in depresyon \u00f6l\u00e7e\u011fi: Ge\u00e7erlik ve g\u00fcvenirlik \u00e7al\u0131\u015fmas\u0131. T\u00fcrk Psikiyatri Dergisi","volume":"2","author":"\u00d6y B.","year":"1991","journal-title":"T\u00fcrk Psikiyatri Dergisi"},{"issue":"34","key":"e_1_2_12_28_1","first-page":"32","article-title":"\u00c7ocuklar I\u00e7in Durumluk\u2010S\u00fcrekli Kayg\u0131 Envanteri Uyarlama, Ge\u00e7erlik Ve G\u00fcvenilirlik \u00c7al\u0131\u015fmas\u0131","volume":"10","author":"\u00d6zusta H. \u015e.","year":"1995","journal-title":"Turk Psikoloji Dergisi"},{"key":"e_1_2_12_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pcl.2009.05.016"},{"issue":"2","key":"e_1_2_12_30_1","first-page":"87","article-title":"\u00c7ocuklar \u0130\u00e7in Ya\u015fam Kalitesi \u00d6l\u00e7e\u011finin 8\u201012 Ya\u015f \u00c7ocuk Formunun Ge\u00e7erlik ve G\u00fcvenirli\u011fi","volume":"15","author":"Memik N. \u00c7.","year":"2008","journal-title":"Cocuk Ve Genclik Ruh Sagligi Dergisi"},{"key":"e_1_2_12_31_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365\u20102230.2010.03965.x"},{"key":"e_1_2_12_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/pde.70066"},{"key":"e_1_2_12_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.18848"},{"key":"e_1_2_12_34_1","doi-asserted-by":"publisher","DOI":"10.2340\/00015555\u20102600"},{"key":"e_1_2_12_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2019.11.064"},{"key":"e_1_2_12_36_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.16225"},{"key":"e_1_2_12_37_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00403\u2010024\u201003719\u20101"},{"key":"e_1_2_12_38_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525\u20101470.2005.22401.x"},{"key":"e_1_2_12_39_1","doi-asserted-by":"publisher","DOI":"10.3390\/children8111057"},{"key":"e_1_2_12_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijwd.2017.11.002"},{"key":"e_1_2_12_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bodyim.2016.10.001"},{"key":"e_1_2_12_42_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2024.0594"},{"key":"e_1_2_12_43_1","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.86171"},{"key":"e_1_2_12_44_1","doi-asserted-by":"publisher","DOI":"10.1177\/12034754231177582"},{"key":"e_1_2_12_45_1","doi-asserted-by":"publisher","DOI":"10.1002\/ski2.73"},{"key":"e_1_2_12_46_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.20247"},{"key":"e_1_2_12_47_1","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/6879412"}],"container-title":["The Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1346-8138.70443","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/1346-8138.70443","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1346-8138.70443","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T05:31:25Z","timestamp":1788154285000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1346-8138.70443"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,21]]},"references-count":46,"alternative-id":["10.1111\/1346-8138.70443"],"URL":"https:\/\/doi.org\/10.1111\/1346-8138.70443","archive":["Portico"],"relation":{},"ISSN":["0385-2407","1346-8138"],"issn-type":[{"value":"0385-2407","type":"print"},{"value":"1346-8138","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,21]]},"assertion":[{"value":"2026-06-19","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-28","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-21","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"1346-8138.70443"}}