{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T17:11:08Z","timestamp":1768324268418,"version":"3.49.0"},"reference-count":20,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2014,8,3]],"date-time":"2014-08-03T00:00:00Z","timestamp":1407024000000},"content-version":"vor","delay-in-days":2,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Microbiology and Immunology"],"published-print":{"date-parts":[[2014,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:label\/><jats:p>As there is a risk of MTCT of HTLV\u20101, the HSGP HTLV\u20101 MTCT was organized in 2011. To determine how many pregnant women are infected with HTLV\u20101 in Hokkaido, which is the northernmost and the second largest island in Japan with a population of 5\u2009467\u2009000 and 39\u2009392 newborns in 2011, the HSGP HTLV\u20101 MTCT asked all facilities that may care for pregnant women in Hokkaido in July 2013 to provide information on the number of pregnant women who underwent screening for anti\u2010HTLV\u20101 antibody using particle agglutination or chemiluminescent enzyme immunoassay, and the numbers of those with positive, equivocal, and negative test results in the screening and confirmation tests using western blotting or PCR methods in 2012, respectively. A total of 111 facilities participated in this study and provided information on 33\u2009617 pregnant women who underwent screening in 2012, corresponding to approximately 85% of all pregnant women who gave birth in Hokkaido in 2012. Of 81 candidates for a confirmation test because of positive (<jats:italic>n<\/jats:italic><jats:italic>\u2009<\/jats:italic>=\u200977) or equivocal (<jats:italic>n<\/jats:italic>\u2009=\u20094) results on screening, 63 (78%) underwent the confirmation test and, finally, 34 (0.1%) and 33\u2009563 (99.8%) women were judged to be HTLV\u20101 carriers and non\u2010carriers, respectively. It was concluded that the prevalence rate of HTLV\u20101 carriers was low, one per 1000 pregnant women in Hokkaido. Approximately 40 infants are born yearly to mothers infected with HTLV\u20101 in Hokkaido.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1348-0421.12165","type":"journal-article","created":{"date-parts":[[2014,6,6]],"date-time":"2014-06-06T19:52:53Z","timestamp":1402084373000},"page":"427-431","source":"Crossref","is-referenced-by-count":10,"title":["Prevalence of human T\u2010lymphotropic virus type 1 carriers among pregnant women in Hokkaido, Japan"],"prefix":"10.1111","volume":"58","author":[{"given":"Takahiro","family":"Yamada","sequence":"first","affiliation":[{"name":"Department of Obstetrics Hokkaido University Graduate School of Medicine N15W7, Kita\u2010ku Sapporo 060\u20108638"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takehiro","family":"Togashi","sequence":"additional","affiliation":[{"name":"Department of Nursing Sapporo City University Geijutsunomori 1\u2010chome, Minami\u2010ku Sapporo 005\u20100864"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroyuki","family":"Tsutsumi","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Sapporo University School of Medicine S1W17, Chuo\u2010ku Sapporo 060\u20100061"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masahiro","family":"Imamura","sequence":"additional","affiliation":[{"name":"Department of Hematology and Oncology Sapporo Hokuyu Hospital 6\u20106\u20105\u20101, Higashi Sapporo, Shiroishi\u2010ku Sapporo 003\u20100006"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hitoshi","family":"Okubo","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Sapporo Maternity Women's Hospital N13W4, Kita\u2010ku Sapporo 001\u20100013"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mihiro","family":"Okabe","sequence":"additional","affiliation":[{"name":"Hokkaido Medical Association Odori W6, Chuo\u2010ku Sapporo 060\u20100061"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noriko","family":"Takamuro","sequence":"additional","affiliation":[{"name":"Hokkaido Association of Midwives 6\u201010\u201010\u20103, Hassamu, Nishi\u2010ku Sapporo 063\u20100826"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kunio","family":"Tashiro","sequence":"additional","affiliation":[{"name":"Department of Neurology Hokuyukai Neurological Hospital 2\u20102\u20104\u201030, Nijuyonken, Nishi\u2010ku Sapporo 063\u20100802"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Koichi","family":"Yano","sequence":"additional","affiliation":[{"name":"Public Health Office City of Sapporo, Maeda 1\u201011, Teine\u2010ku Sapporo 006\u20108612"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nagafumi","family":"Yamamoto","sequence":"additional","affiliation":[{"name":"Hokkaido Prefecture Government E3S3 Obihiro 080\u20108588"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yukiko","family":"Hirakawa","sequence":"additional","affiliation":[{"name":"Hokkaido Nursing Association Kita 6\u20101, Hondori 16\u2010chome, Shiroishi\u2010ku Sapporo 003\u20100027 Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hisanori","family":"Minakami","sequence":"additional","affiliation":[{"name":"Department of Obstetrics Hokkaido University Graduate School of Medicine N15W7, Kita\u2010ku Sapporo 060\u20108638"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,8,3]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.77.12.7415"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.79.6.2031"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2012.00322"},{"key":"e_1_2_8_5_1","unstructured":"YamaguchiK.Guidance for HTLV\u20101 Carriers. Ministry of Health Labour and Welfare Japan. [Cited 18 May 2014.] Available from URL:http:\/\/www.mhlw.go.jp\/bunya\/kenkou\/kekkaku\u2010kansenshou19\/dl\/htlv\u20101_d.pdf[in Japanese]."},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000096011.92542.DA"},{"issue":"3","key":"e_1_2_8_7_1","first-page":"57","article-title":"Primary prevention of HTLV\u20101 in Japan","volume":"11","author":"Hino S.","year":"1997","journal-title":"Leukemia"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0b013e31827efc39"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.2183\/pjab.87.152"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0b013e318263215e"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1447-0756.2011.01653.x"},{"key":"e_1_2_8_12_1","unstructured":"Statistics Bureau Ministry of Internal Affairs and Communications of Japan. [Cited 10 Feb 2014.] Available from URL:http:\/\/www.e\u2010stat.go.jp\/SG1\/estat\/List.do?lid=000001112823."},{"key":"e_1_2_8_13_1","unstructured":"Statistics Bureau Ministry of Internal Affairs and Communications of Japan. [Cited 10 Feb 2014.] Available from URL:http:\/\/www.e\u2010stat.go.jp\/SG1\/estat\/GL08020103.do?_toGL08020103_listID=000001101883requestSender=estat."},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.23181"},{"key":"e_1_2_8_15_1","first-page":"674","article-title":"Milk\u2010borne transmission of HTLV\u2010I from carrier mothers to their children","volume":"78","author":"Kinoshita K.","year":"1987","journal-title":"Jpn J Cancer Res"},{"key":"e_1_2_8_16_1","first-page":"893","article-title":"Epidemiological analysis of the distribution of antibody to adult T\u2010cell leukemia\u2010virus\u2010associated antigen: possible horizontal transmission of adult T\u2010cell leukemia virus","volume":"73","author":"Tajima K.","year":"1982","journal-title":"Gann"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-111-7-555"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1423-0410.1984.tb00083.x"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1537-2995.1989.29189101168.x"},{"key":"e_1_2_8_20_1","first-page":"763","article-title":"Epidemiology of HTLV\u20101 in Hirado Island and virological and immunological investigation of HTLV\u20101 associated pulmonary disease","volume":"30","author":"Kohno S.","year":"1992","journal-title":"Nihon Kyobu Shikkan Gakkai Zasshi [Jpn J Thorac Dis]"},{"key":"e_1_2_8_21_1","volume-title":"Adult T\u2010Cell Leukemia\u2014Pathophysiology, Treatment, and Prevention","author":"Kinoshita K.","year":"1992"}],"container-title":["Microbiology and Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2F1348-0421.12165","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1348-0421.12165","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T14:31:14Z","timestamp":1696170674000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1348-0421.12165"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,8]]},"references-count":20,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2014,8]]}},"alternative-id":["10.1111\/1348-0421.12165"],"URL":"https:\/\/doi.org\/10.1111\/1348-0421.12165","archive":["Portico"],"relation":{},"ISSN":["0385-5600","1348-0421"],"issn-type":[{"value":"0385-5600","type":"print"},{"value":"1348-0421","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,8]]}}}