{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T09:46:17Z","timestamp":1758707177800},"reference-count":30,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2016,8,20]],"date-time":"2016-08-20T00:00:00Z","timestamp":1471651200000},"content-version":"vor","delay-in-days":19,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100005196","name":"Chinese Academy of Agricultural Sciences","doi-asserted-by":"publisher","award":["SKLVEB2015KFKT006","SKLVEB2015KFKT005"],"award-info":[{"award-number":["SKLVEB2015KFKT006","SKLVEB2015KFKT005"]}],"id":[{"id":"10.13039\/501100005196","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Microbiology and Immunology"],"published-print":{"date-parts":[[2016,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:label \/><jats:p>Poultry husbandry is a very important aspect of the agricultural economy in China. However, chicks are often susceptible to infectious disease microorganisms, such as bacteria, viruses and parasites, causing large economic losses in recent years. In the present study, we isolated an <jats:italic>Acinetobacter baumannii<\/jats:italic> strain, CCGGD201101, from diseased chicks in the Jilin Province of China. Regression analyses of virulence and LD<jats:sub>50<\/jats:sub> tests conducted using healthy chicks confirmed that <jats:italic>A. baumannii<\/jats:italic> CCGGD201101, with an LD<jats:sub>50<\/jats:sub> of 1.81 (\u00b10.11)\u2009\u00d7\u200910<jats:sup>4<\/jats:sup> CFU, was more virulent than <jats:italic>A. baumannii<\/jats:italic> ATCC17978, with an LD<jats:sub>50<\/jats:sub> of 1.73 (\u00b10.13)\u2009\u00d7\u200910<jats:sup>7<\/jats:sup> CFU. Moreover, TEM examination showed that the pili of <jats:italic>A. baumannii<\/jats:italic> CCGGD201101 were different from those of ATCC17978. Antibiotic sensitivity analyses showed that <jats:italic>A. baumannii<\/jats:italic> CCGGD201101 was sensitive to rifampicin but resistant to most other antibiotics. These results imply that <jats:italic>A. baumannii<\/jats:italic> strain CCGGD201101 had both virulence enhancement and antibiotic resistance characteristics, which are beneficial for <jats:italic>A. baumannii<\/jats:italic> survival under adverse conditions and enhance fitness and invasiveness in the host. <jats:italic>A. baumannii<\/jats:italic> CCGGD20101, with its high virulence and antimicrobial resistance, may be one of the pathogens causing death of diseased chicks.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1348-0421.12400","type":"journal-article","created":{"date-parts":[[2016,7,11]],"date-time":"2016-07-11T14:01:48Z","timestamp":1468245708000},"page":"533-539","source":"Crossref","is-referenced-by-count":11,"title":["Characterization of a highly virulent and antimicrobial\u2010resistant <i>Acinetobacter baumannii<\/i> strain isolated from diseased chicks in 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