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The resistance spectrum of the 36 strains was measured using a broth dilution method. Class 1 integrons harboring the \u03b2\u2010lactamase gene and mutations in quinolone resistance determining regions were also investigated. All 36 quinolone\u2010resistant <jats:italic>Salmonella<\/jats:italic> Typhimurium strains were found to be multidrug\u2010resistant and the majority of these strains harbored Class 1 integrons. These findings study suggests that strategies for determining resistance spectrums should be implemented with greater urgency.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1348-0421.12476","type":"journal-article","created":{"date-parts":[[2017,3,24]],"date-time":"2017-03-24T12:02:29Z","timestamp":1490356949000},"page":"138-143","source":"Crossref","is-referenced-by-count":5,"title":["Mechanisms of resistance to quinolones in <i>Salmonella<\/i> Typhimurium from patients with infectious diarrhea"],"prefix":"10.1111","volume":"61","author":[{"given":"Jing","family":"Yuan","sequence":"first","affiliation":[{"name":"Emergency Department Beijing Tiantan Hospital Capital Medical University Beijing 100050 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Guo","sequence":"additional","affiliation":[{"name":"Emergency Department Beijing Tiantan Hospital Capital Medical University Beijing 100050 China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,4,11]]},"reference":[{"key":"e_1_2_4_2_1","first-page":"1874","article-title":"Etiological characteristics of diarrhea patients with non\u2010typhoidal Salmonella infections in a general hospital","volume":"24","author":"Lan H.L.","year":"2014","journal-title":"Chin J Nosocomiol"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00108-015-3756-2"},{"key":"e_1_2_4_4_1","first-page":"921","article-title":"Analysis of clinical application of antimicrobial agents in patients with infectious diarrhea","volume":"17","author":"Lin B.T.","year":"2016","journal-title":"Zhejiang Clin Med J"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjid.2012.11.012"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tim.2014.04.007"},{"key":"e_1_2_4_7_1","doi-asserted-by":"crossref","first-page":"981","DOI":"10.3855\/jidc.3817","article-title":"A three\u2010year review of antimicrobial resistance of Salmonella enterica serovars Typhi and Paratyphi A in Pakistan","volume":"13","author":"Qamar F.N.","year":"2014","journal-title":"J Infect Dev Countries"},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.1099\/jmm.0.2008\/001719-0"},{"key":"e_1_2_4_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(95)91906-6"},{"key":"e_1_2_4_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.trstmh.2007.10.003"},{"key":"e_1_2_4_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2011.03552.x"},{"key":"e_1_2_4_12_1","unstructured":"Clinical and Laboratory Standards Institute. 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