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In the present study, <jats:italic>Staphylococcus aureus<\/jats:italic> MTCC\u2010737 showed strong co\u2010aggregation with leptospiral strains (&gt;75%, visual score of\u2009+\u20094) <jats:italic>in vitro<\/jats:italic>. All tested strains of <jats:italic>Leptospira<\/jats:italic> were able to form biofilm with <jats:italic>S. aureus.<\/jats:italic> Scanning electron microscopy analysis revealed intertwined networks of attached cells of <jats:italic>L. interrogans<\/jats:italic> and <jats:italic>S. aureus<\/jats:italic>, thus providing evidence of a matrix\u2010like structure. This phenomenon may have implications in <jats:italic>Leptospira<\/jats:italic> infection, which occurs via cuts and wounds of the skin.<\/jats:p>","DOI":"10.1111\/1348-0421.12679","type":"journal-article","created":{"date-parts":[[2019,5,1]],"date-time":"2019-05-01T01:55:12Z","timestamp":1556675712000},"page":"147-150","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Coaggregation and biofilm formation of <i>Leptospira<\/i> with <i>Staphylococcus aureus<\/i>"],"prefix":"10.1111","volume":"63","author":[{"given":"Kirubakaran","family":"Vinod Kumar","sequence":"first","affiliation":[{"name":"Regional Medical Research Centre (ICMR) WHO Collaborating Centre for Diagnosis, Reference, Research and Training in Leptospirosis Port Blair Andaman and Nicobar Islands India"},{"name":"Department of Microbiology Indian Academy Degree College \u2013Autonomous, Hennur Cross Bengaluru Karnataka 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