{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:39:54Z","timestamp":1787013594034,"version":"build-2736575974"},"reference-count":40,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2020,5,18]],"date-time":"2020-05-18T00:00:00Z","timestamp":1589760000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Microbiology and Immunology"],"published-print":{"date-parts":[[2020,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Liver transplantation (LT) is a potentially curative treatment for terminal stage hepatic diseases. Bacterial infections are the main causes of mortality and morbidity in the early period after LT. Identifying the risk factors could help in minimizing their development. We prospectively investigated the incidence, characteristics, and risk factors of bacterial infections among the recipients during hospitalization after LT and assigned a predictive score. All 389 consecutive adults who underwent LT at the main referral hospital of LT in Iran during 1 year were enrolled prospectively in a cohort study. Infection group consisted of 143 recipients (36.8%). Urinary tract and surgical site infections were the most frequent ones. Gram\u2010negative bacteria were more prevalent than Gram\u2010positive ones. Independent risk factors were female sex (relative risks\u2009=\u20092.13), age \u2264 43.5 years (3.70), hospital stay \u2265 9.5 days (5.22), abdominal reoperation (3.03), vancomycin\u2010resistant Enterococci colonization (5.52), hospitalization 3 months prior to LT (3.25), mechanical ventilation \u226548\u2009hr (4.93), and renal replacement therapies (13.40). We developed a risk score for the prediction of bacterial infections with an area under the receiver operating characteristic curve of 0.85 (95% CI, 0.81\u20130.89) with sensitivity of 88% and specificity of 64%. In the infection group, mortality was higher than in controls (18.9% vs. 2.0%) with longer hospitalization (16 vs. 10 days;\n                    <jats:italic>P<\/jats:italic>\n                    \u2009&lt;\u20090.001). We detected a high rate of bacterial infections leading to longer hospital stay and higher mortality rate. The formulated risk score can help predict bacterial infections; however, it requires clinical validation in further studies.\n                  <\/jats:p>","DOI":"10.1111\/1348-0421.12785","type":"journal-article","created":{"date-parts":[[2020,2,29]],"date-time":"2020-02-29T05:54:37Z","timestamp":1582955677000},"page":"407-415","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Bacterial infections in the early period after liver transplantation in adults: A prospective single\u2010center cohort study"],"prefix":"10.1111","volume":"64","author":[{"given":"Zahra","family":"Jafarpour","sequence":"first","affiliation":[{"name":"Alborzi Clinical Microbiology Research Center, Nemazee Teaching Hospital Shiraz University of Medical Sciences  Shiraz Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8676-4607","authenticated-orcid":false,"given":"Gholamreza","family":"Pouladfar","sequence":"additional","affiliation":[{"name":"Alborzi Clinical Microbiology Research Center, Nemazee Teaching Hospital Shiraz University of Medical Sciences  Shiraz Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seyed Ali","family":"Malek Hosseini","sequence":"additional","affiliation":[{"name":"Shiraz Organ Transplant Center, Abu\u2010Ali Sina Hospital Shiraz University of Medical Sciences  Shiraz Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad","family":"Firoozifar","sequence":"additional","affiliation":[{"name":"Shiraz Organ Transplant Center, Abu\u2010Ali Sina Hospital Shiraz University of Medical Sciences  Shiraz Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peyman","family":"Jafari","sequence":"additional","affiliation":[{"name":"Department of Biostatistics Shiraz University of Medical Sciences  Shiraz Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,5,18]]},"reference":[{"key":"e_1_2_8_2_1","first-page":"145","article-title":"Early postoperative infections after liver transplant","volume":"16","author":"Ayvazoglu Soy EH","year":"2018","journal-title":"Exp Clin Transplant"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v20.i20.6211"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/tid.13001"},{"key":"e_1_2_8_5_1","first-page":"190","article-title":"Urinary tract infections among hospitalized adults in the early post\u2010liver transplant period: prevalence, risk factors, causative agents, and microbial susceptibility","volume":"15","author":"Pouladfar 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