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Despite this characteristic serological profile, misdiagnosis can occur in cases of unexpected or atypical behavior of the serological markers in the bloodstream, or if the true meaning of its expression is not properly investigated, or even if there is a possibility of interference from factors not necessarily linked to the infectious process, in the detection of these markers. This review discusses the influence of these variables on laboratory results for these two serological markers and, therefore, the potential risk of these variables compromising the correct diagnosis of acute infection after recent HBV exposure.<\/jats:p>","DOI":"10.1111\/1348-0421.12943","type":"journal-article","created":{"date-parts":[[2021,9,16]],"date-time":"2021-09-16T11:22:27Z","timestamp":1631791347000},"page":"1-9","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Detection of the serological markers hepatitis B virus surface antigen (HBsAg) and hepatitis B core IgM antibody (anti\u2010HBcIgM) in the diagnosis of acute hepatitis B virus infection after recent exposure"],"prefix":"10.1111","volume":"66","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8909-9091","authenticated-orcid":false,"given":"Rob\u00e9rio Amorim","family":"de Almeida Pond\u00e9","sequence":"first","affiliation":[{"name":"Laboratory of Human Virology, Institute of Tropical Pathology and Public Health Federal University of Goi\u00e1s Goi\u00e2nia Goi\u00e1s Brazil"},{"name":"Secretaria de Estado da Sa\u00fade\u2010SES\/Superintend\u00eancia de Vigil\u00e2ncia em Sa\u00fade\u2010SUVISA\/GO Ger\u00eancia de Vigil\u00e2ncia Epidemiol\u00f3gica\u2010GVE\/Coordena\u00e7\u00e3o de An\u00e1lises e Pesquisas\u2010CAP Goi\u00e2nia Goi\u00e1s Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,10,25]]},"reference":[{"key":"e_1_2_9_2_1","unstructured":"WHO.2021. 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