{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T11:16:14Z","timestamp":1768821374189,"version":"3.49.0"},"reference-count":24,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2024,10,3]],"date-time":"2024-10-03T00:00:00Z","timestamp":1727913600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100007847","name":"Natural Science Foundation of Jilin Province","doi-asserted-by":"publisher","award":["20230203138SF"],"award-info":[{"award-number":["20230203138SF"]}],"id":[{"id":"10.13039\/100007847","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007847","name":"Natural Science Foundation of Jilin Province","doi-asserted-by":"publisher","award":["20220402055GH"],"award-info":[{"award-number":["20220402055GH"]}],"id":[{"id":"10.13039\/100007847","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012226","name":"Fundamental Research Funds for the Central Universities","doi-asserted-by":"publisher","award":["2022\u2010JCXK\u201033"],"award-info":[{"award-number":["2022\u2010JCXK\u201033"]}],"id":[{"id":"10.13039\/501100012226","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Microbiology and Immunology"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Avian metaavulavirus 8 (AMAV\u20108), formerly known as avian paramyxovirus 8 (APMV\u20108), has been detected sporadically in wild birds worldwide since it was first identified in a Canadian goose in 1976. However, the presence of AMAV\u20108 in birds has never been reported in China. To understand the epidemiological situation of AMAV\u20108 and its ability to infect chickens, we conducted a surveillance study and <jats:italic>in vivo<\/jats:italic> analysis of the AMAV\u20108 isolate identified in total of 14,909 clinical samples collected from wild and domestic birds from 2014 to 2022 in China. However, in 2017, only one AMAV\u20108 virus (Y7) was successful isolated from the fresh droppings of a migratory swan goose in Qinghai Lake in Northwest China. Thereafter, we report the complete genome sequence of the Y7 strain with a genome length of 15,342 nucleotides and the Y7 isolate was genetically closely\u2010related to wild bird\u2010origin AMAV\u20108 viruses previously circulated in the United States, Japan, and Kazakhstan. Furthermore, AMAV\u20108 infections of one\u2010day\u2010old specific pathogen\u2010free (SPF) chicks did not induce any clinical signs over the entire observation period but was associated with viral shedding for up to 8 days. Interestingly, although all birds infected with the Y7 strain seroconverted within the first week of infection, virus replication was only detected in the trachea but not in other tissues such as the brain, lung, or heart. Here, we report the complete genome, genetic and biological characterization, replication and pathogenicity analysis in vivo and first detection of AMAV\u20108 in China.<\/jats:p>","DOI":"10.1111\/1348-0421.13175","type":"journal-article","created":{"date-parts":[[2024,10,3]],"date-time":"2024-10-03T08:45:10Z","timestamp":1727945110000},"page":"399-405","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["First detection and biological characterization of an avian metaavulavirus 8 isolated from a migratory swan goose in Qinghai Lake, Northwest China"],"prefix":"10.1111","volume":"68","author":[{"given":"Sijie","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Preventive Veterinary Medicine State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory of Zoonosis Research, Ministry of Education, College of Veterinary Medicine, Jilin University Changchun China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xinxin","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Preventive Veterinary Medicine State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory of Zoonosis Research, Ministry of Education, College of Veterinary Medicine, Jilin University Changchun China"},{"name":"College of Food Science and Engineering Jilin University Changchun China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianjun","family":"Chen","sequence":"additional","affiliation":[{"name":"CAS Key Laboratory of Special Pathogens and Biosafety Wuhan Institute of Virology, Chinese Academy of Sciences Wuhan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weiwen","family":"Yan","sequence":"additional","affiliation":[{"name":"Department of Preventive Veterinary Medicine State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory of Zoonosis Research, Ministry of Education, College of Veterinary Medicine, Jilin University Changchun China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongjin","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Preventive Veterinary Medicine State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory of Zoonosis Research, Ministry of Education, College of Veterinary Medicine, Jilin University Changchun China"},{"name":"School of Life Sciences Changchun Sci-Tech University Changchun Jilin China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weiwei","family":"Chi","sequence":"additional","affiliation":[{"name":"Department of Preventive Veterinary Medicine State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory of Zoonosis Research, Ministry of Education, College of Veterinary Medicine, Jilin University Changchun China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rui","family":"Luo","sequence":"additional","affiliation":[{"name":"Department of Preventive Veterinary Medicine State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory of Zoonosis Research, Ministry of Education, College of Veterinary Medicine, Jilin University Changchun China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xianwen","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Preventive Veterinary Medicine State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory of Zoonosis Research, Ministry of Education, College of Veterinary Medicine, Jilin University Changchun China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yue","family":"Yin","sequence":"additional","affiliation":[{"name":"Department of Preventive Veterinary Medicine State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory of Zoonosis Research, Ministry of Education, College of Veterinary Medicine, Jilin University Changchun China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chuanrong","family":"Dong","sequence":"additional","affiliation":[{"name":"Department of Preventive Veterinary Medicine State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory of Zoonosis Research, Ministry of Education, College of Veterinary Medicine, Jilin University Changchun China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huihui","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Preventive Veterinary Medicine State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory of Zoonosis Research, Ministry of Education, College of Veterinary Medicine, Jilin University Changchun China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bowen","family":"Zheng","sequence":"additional","affiliation":[{"name":"Department of Preventive Veterinary Medicine State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory of Zoonosis Research, Ministry of Education, College of Veterinary Medicine, Jilin University Changchun China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongli","family":"Li","sequence":"additional","affiliation":[{"name":"College of Veterinary Medicine Shanxi Agricultural University Taiyuan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yifei","family":"Liu","sequence":"additional","affiliation":[{"name":"College of Veterinary Medicine Shanxi Agricultural University Taiyuan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tobias","family":"Stoeger","sequence":"additional","affiliation":[{"name":"Institute of Lung Health and Immunity (LHI), Comprehensive Pneumology Center (CPC) Helmholtz Zentrum M\u00fcnchen, Member of the German Center for Lung Research (DZL) Munich Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdul","family":"Wajid","sequence":"additional","affiliation":[{"name":"Department of Biotechnology Balochistan University of Information Technology, Engineering and Management Sciences Quetta Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2416-8003","authenticated-orcid":false,"given":"Aleksandar","family":"Dodovski","sequence":"additional","affiliation":[{"name":"Department for Avian Diseases Faculty of Veterinary Medicine, Ss. 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