{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:40:23Z","timestamp":1787013623663,"version":"build-2736575974"},"reference-count":27,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2024,1,27]],"date-time":"2024-01-27T00:00:00Z","timestamp":1706313600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aus Occup Therapy J"],"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Previous research indicates that children with Paediatric Acute\u2010onset Neuropsychiatric Syndrome (PANS) experience sensory reactivity differences that impact occupational performance. The purpose of this study was to determine whether there are differences in sensory reactivity in these children across two different time points; during exacerbation and during remission, using the Sensory Processing Measure (SPM) Home\u2010Form. The study also sought to investigate whether children with PANS experience sensory differences during remission periods, when compared with SPM Home\u2010Form norms.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A two\u2010period bidirectional case\u2010crossover design was used, and an online assessment was conducted to measure sensory reactivity. Parents of children aged 4.6 to 13.1\u00a0years with a diagnosis of PANS were recruited from various sites across Australia, USA, England, Ireland, Scotland, Canada, and New Zealand. The SPM Home\u2010Form was used to measure sensory reactivity at two time points, when PANS was in remission (T\u2010R) and in exacerbation (T\u2010E). Study entry was permitted at either T\u2010E or T\u2010R. Participant exacerbation status was monitored over a maximum 12\u2010month period, and a follow\u2010up SPM Home\u2010Form was sent when a change in exacerbation status was indicated. A linear mixed model was used to assess the difference between SPM Home\u2010Form norm\u2010referenced scores during exacerbation and remission.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The study included 82 participants, with 80 providing data at study entry, and 27 providing data at follow\u2010up. Results showed a statistically significant decline in performance across the SPM Home\u2010Form domains of Hearing, Social Participation, Planning and Ideas, and Total Sensory Systems T\u2010scores during exacerbation when compared with remission data. Results also demonstrated atypical sensory reactivity across Vision, Hearing, Touch, Balance and Motion, and Total Sensory Systems domains during periods of remission compared with SPM Home\u2010Form norms.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This study found that children with PANS experience significant sensory reactivity differences during exacerbation and remission across multiple sensory domains, with a decline in performance during exacerbation. Where there are occupational performance challenges, occupational therapists should consider administering sensory assessments so that effective intervention plans addressing the unique sensory reactivity needs of children with PANS can be developed.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/1440-1630.12935","type":"journal-article","created":{"date-parts":[[2024,1,27]],"date-time":"2024-01-27T06:39:17Z","timestamp":1706337557000},"page":"475-485","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Sensory processing in children with Paediatric Acute\u2010onset Neuropsychiatric Syndrome"],"prefix":"10.1111","volume":"71","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3072-8663","authenticated-orcid":false,"given":"Michelle J.","family":"Newby","sequence":"first","affiliation":[{"name":"Stepping Stones Therapy for Children  Charlestown New South Wales Australia"},{"name":"Occupational Therapy, College of Health, Medicine and Wellbeing, School of Health Sciences University of Newcastle  Callaghan New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shelly J.","family":"Lane","sequence":"additional","affiliation":[{"name":"Occupational Therapy, College of Health, Medicine and Wellbeing, School of Health Sciences University of Newcastle  Callaghan New South Wales Australia"},{"name":"Department of Occupational Therapy Colorado State University  Fort Collins Colorado USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1321-8899","authenticated-orcid":false,"given":"Kirsti","family":"Haracz","sequence":"additional","affiliation":[{"name":"Occupational Therapy, College of Health, Medicine and Wellbeing, School of Health Sciences University of Newcastle  Callaghan New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janice","family":"Tona","sequence":"additional","affiliation":[{"name":"Rehabilitation Science Department University at Buffalo  Buffalo New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kerrin","family":"Palazzi","sequence":"additional","affiliation":[{"name":"Hunter Medical Research Institute  New Lambton Heights New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Lambkin","sequence":"additional","affiliation":[{"name":"Hunter Medical Research Institute  New Lambton Heights New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,1,27]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40337-022-00707-6"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.books.9780890425596"},{"key":"e_1_2_11_4_1","first-page":"437","volume-title":"Kids can be kids: A childhood occupations approach","author":"Anzalone M.","year":"2012"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8749.2008.03095.x"},{"key":"e_1_2_11_6_1","unstructured":"Bhattacharjya S.(2013).The Impact of Pediatric Acute\u2010onset Neuropsychiatric Syndrome Exacerbations on Daily Functioning(Masters Thesis). 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