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Despite the tight correlation between sleep apnoea and these comorbidities, the mechanisms behind increased cardiovascular risk in <jats:styled-content style=\"fixed-case\">OSA<\/jats:styled-content> remain elusive. Several theories have been postulated, including sympathetic activation, endothelial dysfunction, oxidative stress and inflammation.<\/jats:p><\/jats:list-item>\n\n<jats:list-item><jats:p>The association between <jats:styled-content style=\"fixed-case\">OSA<\/jats:styled-content> and cardiovascular diseases may be rather complicated and compounded by the presence of components of metabolic syndrome, such as obesity, hypertension, diabetes mellitus and dyslipidaemia. The present minireview updates current knowledge with regard to the cardiovascular sequelae of <jats:styled-content style=\"fixed-case\">OSA<\/jats:styled-content> and the mechanisms involved.<\/jats:p><\/jats:list-item>\n<\/jats:list>\n<\/jats:p>","DOI":"10.1111\/1440-1681.12024","type":"journal-article","created":{"date-parts":[[2012,10,20]],"date-time":"2012-10-20T04:16:07Z","timestamp":1350706567000},"page":"995-1003","source":"Crossref","is-referenced-by-count":26,"title":["Obstructive sleep apnoea and cardiovascular complications: perception versus knowledge"],"prefix":"10.1111","volume":"39","author":[{"given":"Joi J","family":"Thomas","sequence":"first","affiliation":[{"name":"Division of Kinesiology and Health &amp; Biomedical Science University of Wyoming College of Health Sciences Laramie WY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun","family":"Ren","sequence":"additional","affiliation":[{"name":"Division of Kinesiology and Health &amp; Biomedical Science University of Wyoming College of Health Sciences Laramie WY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,11,26]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0b013e3182009701"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.98.8.772"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI118235"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2009.05.021"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0031-1273092"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.163.1.2001008"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.101.2.541"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1993.75.4.1439"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.290.14.1906"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.2109080"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.104.3.781"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1586\/erc.10.55"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.165.7.2104126"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.resp.2011.03.015"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2869.2009.00789.x"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmed.2011.01.001"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200306-767OC"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1159\/000228905"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.121.5.1541"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1210\/jcem.82.5.3950"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.166.16.1725"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2011.04.028"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1586\/erc.09.25"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10741-008-9101-2"},{"key":"e_1_2_6_26_1","first-page":"1322","article-title":"Sleep\u2010disordered breathing and cardiovascular disorders","volume":"55","author":"Budhiraja R","year":"2010","journal-title":"Respir. 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