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The aim of the study was to investigate arterial diameters and wall mechanics at multiple arterial sites in these subjects and compare them with controls without a family history of <jats:styled-content style=\"fixed-case\">AAA<\/jats:styled-content>. This study included 118 first\u2010degree relatives of patients with <jats:styled-content style=\"fixed-case\">AAA<\/jats:styled-content> and 66 controls (age: 40\u201380\u00a0years). The abdominal aorta, common carotid artery, common femoral artery, and popliteal artery were investigated by echo\u2010tracking ultrasound. The relatives had no arterial dilatation, but they did tend to have smaller diameters than controls. Relatives had a higher heart rate, diastolic blood pressure, and mean arterial pressure than controls. The distensibility coefficient and the compliance coefficient were decreased in all arteries in male relatives, adjusted for age and smoking; these coefficients were normalized after adjustment for mean arterial pressure and heart rate. Female relatives had a lower compliance coefficient in the abdominal aorta, adjusted for age and smoking. After adjustment for mean arterial pressure and heart rate, the difference disappeared. No general arterial dilatation in relatives without <jats:styled-content style=\"fixed-case\">AAA<\/jats:styled-content> was found, supporting the hypothesis that the dilating diathesis is linked to the aneurysmal manifestation in the abdominal aorta. Although the threat of aneurysmal dilatation and rupture seems to be lacking in these subjects, heart rate, blood pressure, and arterial wall stiffness were all increased, which may indicate a higher risk of developing cardiovascular morbidity and mortality.<\/jats:p>","DOI":"10.1111\/1440-1681.12395","type":"journal-article","created":{"date-parts":[[2015,4,16]],"date-time":"2015-04-16T06:46:59Z","timestamp":1429166819000},"page":"576-581","source":"Crossref","is-referenced-by-count":1,"title":["Increased cardiovascular risk without generalized arterial dilating diathesis in persons who do not have abdominal aortic aneurysm but who are first\u2010degree relatives of abdominal aortic aneurysm patients"],"prefix":"10.1111","volume":"42","author":[{"given":"Rachel","family":"De Basso","sequence":"first","affiliation":[{"name":"Division of Medical Diagnostics Department of Clinical Physiology Region J\u00f6nk\u00f6ping County J\u00f6nk\u00f6ping Sweden"},{"name":"Department of Natural 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