{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T19:04:37Z","timestamp":1790190277789,"version":"4.1.0"},"reference-count":19,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2015,6,4]],"date-time":"2015-06-04T00:00:00Z","timestamp":1433376000000},"content-version":"vor","delay-in-days":3,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Jinan City Health Bureau of Science and Technology Program","award":["2008-61"],"award-info":[{"award-number":["2008-61"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clin Exp Pharma Physio"],"published-print":{"date-parts":[[2015,6]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>This study aimed to evaluate the changes in left and right ventricular functions of children with obstructive sleep apnoea\u2013hypopnoea syndrome (<jats:styled-content style=\"fixed-case\">OSAHS<\/jats:styled-content>) and to determine the efficacy of surgical treatment for <jats:styled-content style=\"fixed-case\">OSAHS<\/jats:styled-content> in children. The subjects included 20 normal controls and 55 children of <jats:styled-content style=\"fixed-case\">OSAHS<\/jats:styled-content> with adenoid and\/or tonsil hypertrophy diagnosed by polysomnography (<jats:styled-content style=\"fixed-case\">PSG<\/jats:styled-content>). We divided the children with <jats:styled-content style=\"fixed-case\">OSAHS<\/jats:styled-content> into the mild group, moderate group and severe group of <jats:styled-content style=\"fixed-case\">OSAHS<\/jats:styled-content> according to the condition of apnoea\u2013hypopnoea index (<jats:styled-content style=\"fixed-case\">AHI<\/jats:styled-content>) and the lowest of\u00a0oxygen saturation (<jats:styled-content style=\"fixed-case\">LS<\/jats:styled-content>aO<jats:sub>2<\/jats:sub>). In mitral annulus,the Va values were increased in moderate and severe <jats:styled-content style=\"fixed-case\">OSAHS<\/jats:styled-content> (<jats:italic>P<\/jats:italic>\u00a0&gt;\u00a00.05), and the Ve\/Va values were decreased in the severe group (<jats:italic>P<\/jats:italic>\u00a0&gt;\u00a00.05), while the Vs values were not changed (<jats:italic>P<\/jats:italic>\u00a0&gt;\u00a00.05). In tricuspid annulus, the Vs values were decreased in moderate and severe <jats:styled-content style=\"fixed-case\">OSAHS<\/jats:styled-content> (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.05), while the Ve, Va and Ve\/Va values were not changed (<jats:italic>P<\/jats:italic>\u00a0&gt;\u00a00.05). Six months after adenoidectomy and\/or tonsillectomy, mitral Va values were decreased and tricuspid Vs values were increased significantly (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.05), and <jats:styled-content style=\"fixed-case\">AHI<\/jats:styled-content> was decreased and <jats:styled-content style=\"fixed-case\">LS<\/jats:styled-content>aO<jats:sub>2<\/jats:sub> was significantly increased (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.05). Compared with the control group, no difference was found in the above parameters (<jats:italic>P<\/jats:italic>\u00a0&gt;\u00a00.05). The left ventricular diastolic function and the right ventricular systolic function of children with moderate to severe <jats:styled-content style=\"fixed-case\">OSAHS<\/jats:styled-content> are decreased to varying degrees at an early stage. Mitral annular and tricuspid annular velocity detected by quantitative tissue velocity imaging (<jats:styled-content style=\"fixed-case\">QTVI<\/jats:styled-content>) could sensitively reflect the early changes of left and right ventricular function. Adenoidectomy and\/or tonsillectomy were\u00a0effective methods to treat childhood <jats:styled-content style=\"fixed-case\">OSAHS<\/jats:styled-content>, which could reverse myocardial dysfunction.<\/jats:p>","DOI":"10.1111\/1440-1681.12408","type":"journal-article","created":{"date-parts":[[2015,4,23]],"date-time":"2015-04-23T06:13:08Z","timestamp":1429769588000},"page":"602-608","source":"Crossref","is-referenced-by-count":3,"title":["Quantitative tissue velocity imaging evaluation of ventricular function in obstructive sleep apnoea\u2013hypopnoea syndrome in children"],"prefix":"10.1111","volume":"42","author":[{"given":"Hong","family":"Mu","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology Qilu Children's Hospital of Shandong University Jinan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junjie","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery Provincial Hospital Affiliated to Shandong University Jinan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kebo","family":"Gong","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology Qilu Children's Hospital of Shandong University Jinan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dongmei","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology Qilu Children's Hospital of Shandong University Jinan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianji","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology Qilu Children's Hospital of Shandong University Jinan China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,6,4]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02713925"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.106.085175"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa043104"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.97.21.2154"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pcad.2008.03.002"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.107.099762"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200309-1305OC"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2009.01.044"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.79.6.1237"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200411-1597OC"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0030-6665(05)70125-0"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1681.2004.04081.x"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2008.07.004"},{"key":"e_1_2_7_15_1","first-page":"1676","article-title":"Value of quantitative tissue velocity imaging in the evaluation of cardiac function and diagnosis of left heart failure","volume":"87","author":"Qiao W","year":"2007","journal-title":"Zhonghua Yi Xue Za Zhi"},{"key":"e_1_2_7_16_1","first-page":"293","article-title":"Heart failure and respiratory sleep disorders","volume":"95","author":"Pellerin D","year":"2002","journal-title":"Arch. 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