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The etiology of hypertension, however, includes a complex network involved in central and peripheral blood pressure control. Recently, the hyperactivity of the sympathetic nervous system in protein\u2010restricted rats has been reported. Studies have shown that protein malnutrition during pregnancy and\/or lactation alters blood pressure control through mechanisms that include central sympathetic\u2010respiratory dysfunctions and epigenetic modifications, which may contribute to adult hypertension. Thus, this review will discuss the historical context, new evidences of neurogenic disruption in respiratory\u2010sympathetic activities and possible epigenetic mechanisms involved in maternal protein malnutrition induced\u2010 hypertension.<\/jats:p>","DOI":"10.1111\/1440-1681.12892","type":"journal-article","created":{"date-parts":[[2017,11,22]],"date-time":"2017-11-22T06:02:42Z","timestamp":1511330562000},"page":"422-429","source":"Crossref","is-referenced-by-count":19,"title":["Maternal protein malnutrition induced\u2010hypertension: New evidence about the autonomic and respiratory dysfunctions and epigenetic mechanisms"],"prefix":"10.1111","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4696-3809","authenticated-orcid":false,"given":"Jos\u00e9 Luiz","family":"de Brito Alves","sequence":"first","affiliation":[{"name":"Department of Nutrition Health Sciences Center Federal University of Para\u00edba UFPB  Jo\u00e3o Pessoa 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