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Chromium deficiency is correlated with elevation in cardiometabolic risk, which results from increased inflammation. This systematic review was conducted to discover the potential roles of chromium on\u00a0inflammatory\u00a0biomarkers. Eligible studies were all in vitro, animal and human studies published in English\u2010language journals from inception until October 2018. PubMed, Scopus, Embase, ProQuest and Google Scholar databases were searched to fined interventional studies from the effects of chromium on inflammatory\u00a0biomarkers such as tumour necrosis factor a (<jats:styled-content style=\"fixed-case\">TNF<\/jats:styled-content>\u2010a), C\u2010reactive protein (<jats:styled-content style=\"fixed-case\">CRP<\/jats:styled-content>), interleukins, monocyte chemoattractant protein\u20131 (<jats:styled-content style=\"fixed-case\">MCP<\/jats:styled-content>\u20101), intercellular adhesion molecule\u20101 (<jats:styled-content style=\"fixed-case\">ICAM<\/jats:styled-content>\u20101) and adipocytokines in hyperglycaemia and diabetes. Out of 647 articles found in the search, only 14 articles were eligible for analysis, three in vitro studies, eight animal studies and three human studies. Twelve of the 14 studies included in this review, chromium significantly decreased inflammatory factors. The findings of this review indicate, based on <jats:italic>in vitro<\/jats:italic> and <jats:italic>in vivo<\/jats:italic> studies, that chromium might have potential anti\u2010inflammatory properties, but some of the studies did not show anti\u2010inflammatory effects for chromium (two studies). There are only three studies in humans with controversial results. Therefore, more consistent randomized double\u2010blind controlled trials are needed to reach relevant clinical recommendations, as well as to determine the precise mechanism, of chromium on inflammation in diabetes.<\/jats:p>","DOI":"10.1111\/1440-1681.13144","type":"journal-article","created":{"date-parts":[[2019,7,22]],"date-time":"2019-07-22T16:30:04Z","timestamp":1563813004000},"page":"975-983","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":35,"title":["Potential roles of chromium on inflammatory biomarkers in diabetes: A Systematic"],"prefix":"10.1111","volume":"46","author":[{"given":"Fardin","family":"Moradi","sequence":"first","affiliation":[{"name":"Faculty of Nutrition and Food Sciences Tabriz University of Medical Sciences Tabriz 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