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Type 1 interferons (IFN\u2010I) are a family cytokines of the early innate immune response to viruses that are being tested against SARS\u2010CoV\u20102. However, coronaviruses similar to SARS\u2010CoV\u20102 can suppress host IFN\u2010I antiviral responses. Retinoids are a family molecules related to vitamin A that possess robust immune\u2010modulating properties, including the ability to increase and potentiate the actions of IFN\u2010I. Therefore, adjuvants such as retinoids, capable of increasing IFN\u2010I\u2010mediated antiviral responses, should be tested in combinations of IFN\u2010I and antiviral drugs in pre\u2010clinical studies of SARS\u2010CoV\u20102.<\/jats:p>","DOI":"10.1111\/1440-1681.13354","type":"journal-article","created":{"date-parts":[[2020,5,27]],"date-time":"2020-05-27T09:05:27Z","timestamp":1590570327000},"page":"1765-1767","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":60,"title":["A role for retinoids in the treatment of COVID\u201019?"],"prefix":"10.1111","volume":"47","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1297-3582","authenticated-orcid":false,"given":"Steven E.","family":"Trasino","sequence":"first","affiliation":[{"name":"School of Urban Public Health Hunter College City University of New York New York NY 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