{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T10:53:26Z","timestamp":1770288806722,"version":"3.49.0"},"reference-count":120,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2021,5,29]],"date-time":"2021-05-29T00:00:00Z","timestamp":1622246400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clin Exp Pharma Physio"],"published-print":{"date-parts":[[2021,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Crocodile blood has long been used as a traditional medicine in many Asian countries to treat diseases such as asthma, allergies, and many others. Yet, only recently has the safety and effectiveness of using crocodile blood as a medicine been examined using modern scientific methods; with both conserved and novel active components identified from crocodile blood. Further <jats:italic>in vitro<\/jats:italic> and <jats:italic>in vivo<\/jats:italic> investigations found that crocodile blood can have a wide range of beneficial effects, including antimicrobial, antiviral, anti\u2010oxidative, anti\u2010inflammatory, antitumour effects, anti\u2010anaemia, and enhancement of wound healing. A systematic research of literature published in English\u2010language journals up to April 2020 was conducted in PubMed, Google Scholar, and Web of Science. Based on the biological and chemical knowledge of crocodile immunity and crocodile blood, this article aims to: provide a critical review on the proposed properties of crocodile blood, identify the knowledge gap and offer some insights for future investigations regarding the use of crocodile blood as a medication or dietary supplement.<\/jats:p>","DOI":"10.1111\/1440-1681.13524","type":"journal-article","created":{"date-parts":[[2021,5,14]],"date-time":"2021-05-14T06:16:25Z","timestamp":1620972985000},"page":"1043-1058","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Potential of crocodile blood as a medication and dietary supplement: A systemic review"],"prefix":"10.1111","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1366-6990","authenticated-orcid":false,"given":"Chui Yiu Bamboo","family":"Chook","sequence":"first","affiliation":[{"name":"School of Life Sciences Faculty of Science The Chinese University of Hong Kong  Hong Kong China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francis M.","family":"Chen","sequence":"additional","affiliation":[{"name":"School of Life Sciences Faculty of Science The Chinese University of Hong Kong  Hong Kong China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fung Ping","family":"Leung","sequence":"additional","affiliation":[{"name":"School of Life Sciences Faculty of Science The Chinese University of Hong Kong  Hong Kong China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhen\u2010Yu","family":"Chen","sequence":"additional","affiliation":[{"name":"School of Life Sciences Faculty of Science The Chinese University of Hong Kong  Hong Kong China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4514-3780","authenticated-orcid":false,"given":"Wing Tak","family":"Wong","sequence":"additional","affiliation":[{"name":"School of Life Sciences Faculty of Science The Chinese University of Hong Kong  Hong Kong China"},{"name":"State Key Laboratory of Agrobiotechnology The Chinese University of Hong Kong  Hong Kong China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,5,29]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/qjmed\/hcg121"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1067\/mai.2000.109432"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1096\u20104959(03)00256\u20102"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1645\/GE\u20103382"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.antiviral.2004.12.007"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.3390\/ph7060723"},{"key":"e_1_2_13_8_1","first-page":"437","volume-title":"The Quarterly Review of Biology","author":"Wake DB","year":"1971"},{"issue":"1","key":"e_1_2_13_9_1","first-page":"68","article-title":"Siamese Crocodile Crocodylus siamensis","volume":"41","author":"Simpson BK","year":"2010","journal-title":"Herpetological Rev"},{"key":"e_1_2_13_10_1","first-page":"506","article-title":"Population size, demography and feeding preferences of the Siamese crocodile Crocodylus siamensis (Schneider, 1801) in the Mesangat Swamp in Kalimantan, Indonesia","volume":"66","author":"Behler N","year":"2018","journal-title":"Raffles Bull Zool"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/aqc.2473"},{"key":"e_1_2_13_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/zoo.20418"},{"key":"e_1_2_13_13_1","unstructured":"ChaeychomsriW SiruntawinetiJ ChaeychomsriS HengsawadiD CuptapanY RungtaweechaiW.Successful development and commercialization of freeze\u2010dried crocodile blood product.2013:569\u2010576.https:\/\/doi.org\/10.1017\/CBO9781107415324.004. In: The 39th Congress on Science and Technology of Thailand."},{"key":"e_1_2_13_14_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.i3763"},{"key":"e_1_2_13_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00280\u2010017\u20103410\u2010x"},{"key":"e_1_2_13_16_1","doi-asserted-by":"publisher","DOI":"10.3747\/co.26.4855"},{"key":"e_1_2_13_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.exppara.2017.09.008"},{"key":"e_1_2_13_18_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v18.i7.704"},{"key":"e_1_2_13_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12010\u2010011\u20109482\u2010x"},{"key":"e_1_2_13_20_1","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/44.3.416"},{"issue":"1","key":"e_1_2_13_21_1","first-page":"70","article-title":"Isolation of lysozyme like protein from crocodile leukocyte extract (Crocodylus siamensis)","volume":"7","author":"Pata S","year":"2007","journal-title":"KMITL Sci Technol J"},{"key":"e_1_2_13_22_1","doi-asserted-by":"publisher","DOI":"10.1038\/ja.2013.114"},{"key":"e_1_2_13_23_1","doi-asserted-by":"publisher","DOI":"10.4014\/jmb.1601.01054"},{"key":"e_1_2_13_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10930\u2010016\u20109662\u20101"},{"key":"e_1_2_13_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/jam.13539"},{"key":"e_1_2_13_26_1","doi-asserted-by":"publisher","DOI":"10.4014\/jmb.1603.03046"},{"key":"e_1_2_13_27_1","doi-asserted-by":"publisher","DOI":"10.4014\/jmb.1802.02027"},{"key":"e_1_2_13_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/jfbc.12503"},{"key":"e_1_2_13_29_1","doi-asserted-by":"publisher","DOI":"10.1134\/S0003683819050144"},{"key":"e_1_2_13_30_1","doi-asserted-by":"publisher","DOI":"10.1163\/156853809787392676"},{"key":"e_1_2_13_31_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740\u20100929.2010.00752.x"},{"issue":"7","key":"e_1_2_13_32_1","article-title":"Crocodylus siamensis serum and macrophage phagocytic activity","volume":"94","author":"Aree K","year":"2011","journal-title":"J Med Assoc Thai"},{"key":"e_1_2_13_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.dci.2010.12.011"},{"key":"e_1_2_13_34_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10930\u2010012\u20109424\u20107"},{"key":"e_1_2_13_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbpb.2012.08.002"},{"key":"e_1_2_13_36_1","doi-asserted-by":"publisher","DOI":"10.1186\/1476\u20100711\u201011\u201022"},{"key":"e_1_2_13_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmcl.2013.06.005"},{"key":"e_1_2_13_38_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0000000000001159"},{"key":"e_1_2_13_39_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10930\u2010014\u20109581\u2010y"},{"key":"e_1_2_13_40_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10753\u2010016\u20100471\u20107"},{"issue":"3","key":"e_1_2_13_41_1","first-page":"800","article-title":"Proteomics profiling and inflammatory factor gene expression in LPS\u2010stimulated RAW 264.7 cells treated with Crocodylus siamensis hemoglobin","volume":"44","author":"Jangpromma N","year":"2017","journal-title":"Chiang Mai J Sci"},{"key":"e_1_2_13_42_1","doi-asserted-by":"publisher","DOI":"10.1002\/bab.1628"},{"issue":"3","key":"e_1_2_13_43_1","first-page":"627","article-title":"Comparisons of anti\u2010inflammatory activity of crocodile (Crocodylus siamensis) blood extract","volume":"41","author":"Kommanee J","year":"2014","journal-title":"Chiang Mai J Sci"},{"issue":"5","key":"e_1_2_13_44_1","first-page":"915","article-title":"Antioxidant and anti\u2010inflammatory activities of the siamese crocodile (Crocodylus siamensis) hemoglobin hydrolysate derived from trypsin and papain hydrolysis","volume":"46","author":"Lueangsakulthai J","year":"2019","journal-title":"Chiang Mai J Sci"},{"key":"e_1_2_13_45_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13765\u2010019\u20100488\u20103"},{"key":"e_1_2_13_46_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10930\u2010011\u20109372\u20107"},{"key":"e_1_2_13_47_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10930\u2010013\u20109536\u20108"},{"issue":"3","key":"e_1_2_13_48_1","first-page":"1359","article-title":"Antioxidant properties of Crocodylus siamensis blood components on H2O2\u2010induced human skin fibroblast cells","volume":"45","author":"Jangpromma N","year":"2018","journal-title":"Chiang Mai J Sci"},{"key":"e_1_2_13_49_1","doi-asserted-by":"publisher","DOI":"10.1002\/tox.22108"},{"key":"e_1_2_13_50_1","doi-asserted-by":"publisher","DOI":"10.1002\/tox.22138"},{"key":"e_1_2_13_51_1","doi-asserted-by":"publisher","DOI":"10.3892\/or.2016.4914"},{"key":"e_1_2_13_52_1","doi-asserted-by":"publisher","DOI":"10.21873\/invivo.11356"},{"key":"e_1_2_13_53_1","doi-asserted-by":"publisher","DOI":"10.4014\/jmb.1712.12002"},{"key":"e_1_2_13_54_1","doi-asserted-by":"publisher","DOI":"10.1002\/tox.22584"},{"key":"e_1_2_13_55_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.etap.2018.07.007"},{"key":"e_1_2_13_56_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcp.28774"},{"issue":"1","key":"e_1_2_13_57_1","first-page":"42","article-title":"Effectiveness in the Treatment of Iron Deficiency Anemia in Sprague\u2010Dawley Rats Using Freeze\u2010 Dried Crocodile Blood","volume":"4","author":"Chaeychomsri W","year":"2015","journal-title":"Int J Life Sci Biotechnol Pharma Res"},{"key":"e_1_2_13_58_1","doi-asserted-by":"publisher","DOI":"10.1079\/PAVSNNR20127067"},{"key":"e_1_2_13_59_1","volume-title":"Immunology","author":"Kindt TJ","year":"2006"},{"key":"e_1_2_13_60_1","doi-asserted-by":"publisher","DOI":"10.1242\/jeb.038315"},{"key":"e_1_2_13_61_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.dci.2017.11.018"},{"key":"e_1_2_13_62_1","doi-asserted-by":"publisher","DOI":"10.1002\/bab.1709"},{"key":"e_1_2_13_63_1","doi-asserted-by":"publisher","DOI":"10.1007\/978\u20101\u201060761\u2010594\u20101_10"},{"key":"e_1_2_13_64_1","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.16743"},{"key":"e_1_2_13_65_1","doi-asserted-by":"publisher","DOI":"10.1016\/0300\u20109629(79)90591\u20107"},{"key":"e_1_2_13_66_1","first-page":"1","article-title":"Blood chemestry of reptiles: physiological and evolutionary aspects","volume":"3","author":"Dessauer HC","year":"1970","journal-title":"Biology of the Reptilia"},{"key":"e_1_2_13_67_1","unstructured":"ThompsonKS WalkerCCF SchlegelML.Ascorbic acid vitamin E vitamin A and trace elements in serum of zoo crocodilians.2013. In:Proceedings of the Tenth Conference on Zoo and Wildlife Nutrition. Salt Lake City UT;https:\/\/nagonline.net\/1342\/ascorbic\u2010acid\u2010vitamin\u2010e\u2010vitamin\u2010trace\u2010elements\u2010serum\u2010zoo\u2010crocodilians\/"},{"key":"e_1_2_13_68_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajplegacy.1967.213.5.1183"},{"key":"e_1_2_13_69_1","doi-asserted-by":"publisher","DOI":"10.1016\/0009\u20108981(57)90105\u20105"},{"key":"e_1_2_13_70_1","doi-asserted-by":"publisher","DOI":"10.1016\/0140\u20106736(91)91371\u2010Z"},{"key":"e_1_2_13_71_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)51432-0"},{"key":"e_1_2_13_72_1","doi-asserted-by":"publisher","DOI":"10.1093\/clinchem\/20.9.1141"},{"key":"e_1_2_13_73_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021\u20109258(18)74667\u2010X"},{"key":"e_1_2_13_74_1","doi-asserted-by":"publisher","DOI":"10.1039\/C4MT00148F"},{"key":"e_1_2_13_75_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)75023-0"},{"key":"e_1_2_13_76_1","doi-asserted-by":"publisher","DOI":"10.5851\/kosfa.2017.37.2.228"},{"key":"e_1_2_13_77_1","doi-asserted-by":"publisher","DOI":"10.4141\/cjas77\u2010094"},{"issue":"4","key":"e_1_2_13_78_1","first-page":"1334","article-title":"In vitro anti\u2010aging activities of crocodile (Crocodylus siamensis) blood extracts","volume":"44","author":"Manosroi J","year":"2017","journal-title":"Chiang Mai J Sci"},{"key":"e_1_2_13_79_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0167\u20104838(00)00038\u20108"},{"key":"e_1_2_13_80_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbalip.2007.12.001"},{"key":"e_1_2_13_81_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11033\u2010012\u20101997\u2010x"},{"key":"e_1_2_13_82_1","doi-asserted-by":"publisher","DOI":"10.1038\/nri2333"},{"key":"e_1_2_13_83_1","doi-asserted-by":"publisher","DOI":"10.1093\/database\/bar048"},{"key":"e_1_2_13_84_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcmm.13797"},{"key":"e_1_2_13_85_1","doi-asserted-by":"publisher","DOI":"10.2217\/fmb.15.151"},{"key":"e_1_2_13_86_1","doi-asserted-by":"publisher","DOI":"10.1038\/cddis.2017.52"},{"key":"e_1_2_13_87_1","doi-asserted-by":"publisher","DOI":"10.1038\/sigtrans.2017.23"},{"key":"e_1_2_13_88_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2019.104290"},{"key":"e_1_2_13_89_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cyto.2020.155224"},{"key":"e_1_2_13_90_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V95.12.3823"},{"key":"e_1_2_13_91_1","doi-asserted-by":"publisher","DOI":"10.4161\/cc.6.14.4438"},{"key":"e_1_2_13_92_1","doi-asserted-by":"publisher","DOI":"10.1080\/08820139.2019.1566355"},{"key":"e_1_2_13_93_1","doi-asserted-by":"publisher","DOI":"10.2174\/187221309787158371"},{"key":"e_1_2_13_94_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2020.110729"},{"key":"e_1_2_13_95_1","doi-asserted-by":"publisher","DOI":"10.1139\/Z07\u2010020"},{"key":"e_1_2_13_96_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2005.12.019"},{"key":"e_1_2_13_97_1","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2009.2974"},{"key":"e_1_2_13_98_1","first-page":"309","volume-title":"Nonmammalian Animal Models for Biomedical Research","author":"Reischi E","year":"1989"},{"key":"e_1_2_13_99_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0138111"},{"key":"e_1_2_13_100_1","doi-asserted-by":"publisher","DOI":"10.3109\/10731199809118943"},{"key":"e_1_2_13_101_1","doi-asserted-by":"publisher","DOI":"10.1016\/0076\u20106879(90)86118\u2010F"},{"key":"e_1_2_13_102_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms20153675"},{"key":"e_1_2_13_103_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2014.00117"},{"key":"e_1_2_13_104_1","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.112.679662"},{"key":"e_1_2_13_105_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00394\u2010013\u20100535\u20105"},{"key":"e_1_2_13_106_1","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2009.2826"},{"key":"e_1_2_13_107_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2012.11.003"},{"key":"e_1_2_13_108_1","doi-asserted-by":"publisher","DOI":"10.1038\/373244a0"},{"key":"e_1_2_13_109_1","doi-asserted-by":"publisher","DOI":"10.1089\/dna.2012.1897"},{"key":"e_1_2_13_110_1","doi-asserted-by":"publisher","DOI":"10.1177\/1010428317694320"},{"key":"e_1_2_13_111_1","doi-asserted-by":"publisher","DOI":"10.1634\/theoncologist.11\u20104\u2010342"},{"key":"e_1_2_13_112_1","series-title":"Current Topics in Microbiology and Immunology","first-page":"19","volume-title":"Therapeutic Kinase Inhibitors","author":"Kim WY","year":"2011"},{"key":"e_1_2_13_113_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00262\u2010014\u20101521\u20103"},{"key":"e_1_2_13_114_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature07039"},{"key":"e_1_2_13_115_1","doi-asserted-by":"publisher","DOI":"10.3390\/antiox7080098"},{"key":"e_1_2_13_116_1","unstructured":"National Heart Lung and Blood Institute.Iron\u2010Deficiency Anemia | National Heart Lung and Blood Institute (NHLBI).US Department of Health & Human Services. 2019: Iron\u2010Deficiency Anemia.https:\/\/www.nhlbi.nih.gov\/health\u2010topics\/iron\u2010deficiency\u2010anemia%0Ahttps:\/\/www.nhlbi.nih.gov\/health\u2010topics\/iron\u2010deficiency\u2010anemia%0Ahttps:\/\/www.nhlbi.nih.gov\/health\u2010topics\/espanol\/epoc%0Ahttps:\/\/www.nhlbi.nih.gov\/health\u2010topics\/iron\u2010deficiency\u2010anemia"},{"key":"e_1_2_13_117_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0271\u20105317(88)80021\u20106"},{"key":"e_1_2_13_118_1","unstructured":"NIH Office of Dietary Supplements.Iron \u2013 Health Professional Fact Sheet. National Institutes of Health Office of Dietary Supplements;2018.https:\/\/ods.od.nih.gov\/factsheets\/Iron\u2010HealthProfessional\/%0Ahttps:\/\/ods.od.nih.gov\/factsheets\/Iron\u2010HealthProfessional\/%0Ahttps:\/\/ods.od.nih.gov\/factsheets\/Iron\u2010HealthProfessional\/%0Ahttps:\/\/ods.od.nih.gov\/factsheets\/Iron\u2010HealthProfessional\/%0Ahttps:\/\/ods"},{"key":"e_1_2_13_119_1","unstructured":"SiruntawinetiJ ChaeychomsriW ChaeychomsriS.Reduction of Blood Gluocse level in Diabetic Spraque Dawley Rats Supplemented with Freeze\u2010dried Crocodile Serum. In:The 39th Congress on Science and Technology of Thailand.2013:926\u2010929."},{"key":"e_1_2_13_120_1","doi-asserted-by":"publisher","DOI":"10.1113\/expphysiol.1975.sp002299"},{"key":"e_1_2_13_121_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)75118-1"}],"container-title":["Clinical and Experimental Pharmacology and Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1440-1681.13524","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/1440-1681.13524","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1440-1681.13524","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,22]],"date-time":"2025-01-22T05:31:16Z","timestamp":1737523876000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1440-1681.13524"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5,29]]},"references-count":120,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2021,8]]}},"alternative-id":["10.1111\/1440-1681.13524"],"URL":"https:\/\/doi.org\/10.1111\/1440-1681.13524","archive":["Portico"],"relation":{},"ISSN":["0305-1870","1440-1681"],"issn-type":[{"value":"0305-1870","type":"print"},{"value":"1440-1681","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,5,29]]},"assertion":[{"value":"2021-03-22","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-05-10","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-05-29","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}