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The only causal therapeutic strategy is specific oral immunotherapy. An increasing amount of data confirms this therapy's effectiveness and safety, but the results remain inconclusive due to the lack of long\u2010term follow\u2010up. In this state\u2010of\u2010the\u2010art review, we briefly summarise the latest placebo\u2010controlled randomised controlled trials on oral immunotherapy (OIT) to treat food allergy. During the paper's review, we asked the following questions: does the therapy permanently increase the amount of allergen consumed without symptoms? Does it significantly increase or decrease the occurrence of severe systemic reactions \u2013 requiring the administration of adrenaline or hospitalisation? Many authors describe outcomes such as an increase in the amount of allergen that can be safely ingested; however, significant clinical benefits such as decreased hospitalisations or anaphylaxis incidence are rarely included in the results. To date, there is no unified protocol of therapy, which makes comparisons between studies difficult because of significant differences in types, doses, and routes of administration of the allergen, timeline for up\u2010dosing and maintenance, duration of the therapy, and primary outcomes of OIT.<\/jats:p>","DOI":"10.1111\/1440-1681.13607","type":"journal-article","created":{"date-parts":[[2021,10,30]],"date-time":"2021-10-30T12:40:32Z","timestamp":1635597632000},"page":"191-201","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Oral immunotherapy in children with a food allergy\u2014Where do we stand? \u2013 Review"],"prefix":"10.1111","volume":"49","author":[{"given":"Kaja","family":"Pulik","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Pulmonary Diseases and Allergy Medical University of Warsaw Warsaw 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