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Speech intervention is necessary to eliminate these disorders. There is, however, currently no consensus on the most effective speech therapy approach to eliminate the different subtypes of compensatory cleft speech disorders.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p>To compare the immediate, short\u2010 and long\u2010term effects of three well\u2010defined speech intervention approaches (i.e., a motor\u2013phonetic approach, a linguistic\u2013phonological approach and a combined phonetic\u2013phonological approach) on the speech and health\u2010related quality of life (HRQoL) in Belgian Dutch\u2010speaking children with cleft palate with or without cleft lip (CP\u00b1L) and different subtypes of compensatory speech disorders (i.e., anterior oral cleft speech characteristics (CSCs), posterior oral CSCs or non\u2010oral CSCs). Besides, the perceived acceptability of these three speech intervention approaches will be investigated from the perspectives of caregivers and children with a CP\u00b1L.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods &amp; Procedures<\/jats:title><jats:p>A two\u2010centre longitudinal randomized sham\u2010controlled trial was used. Children were randomly assigned to one of the three intervention programmes and received 10 h of speech intervention divided over 2 weeks. Block randomization was used, stratified by age and gender. Primary outcome measures included perceptual speech outcomes. Secondary outcome measures included patient\u2010reported outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Outcomes &amp; Results<\/jats:title><jats:p>The results of this trial will provide speech\u2013language pathologists evidence\u2010based guidelines to better tailor intervention approaches to the specific needs of a child with a defined compensatory speech disorder.<\/jats:p><\/jats:sec><jats:sec><jats:title>WHAT THIS PAPER ADDS<\/jats:title><jats:sec><jats:title>What is already known on this subject<\/jats:title><jats:p>Speech therapy approaches to address cleft palate speech disorders are broadly divided into two categories: motor\u2013phonetic interventions and linguistic\u2013phonological interventions. Some limited evidence demonstrated the positive effects of these approaches in eliminating compensatory cleft speech disorders. Different studies have reported inter\u2010individual variation, suggesting that one child may benefit more from a particular intervention approach than the other child. Perhaps this variation can be attributed to the specific subtype of compensatory speech disorder (i.e., anterior oral CSC, posterior oral CSC or non\u2010oral CSC).<\/jats:p><\/jats:sec><jats:sec><jats:title>What this paper adds to existing knowledge<\/jats:title><jats:p>This paper describes a randomized sham\u2010controlled trial that compared the immediate, short\u2010 and long\u2010term effects of three well\u2010defined speech intervention approaches (i.e., a motor\u2013phonetic approach, a linguistic\u2013phonological approach and a combined phonetic\u2013phonological approach) on the speech and HRQoL in Belgian Dutch\u2010speaking children with CP\u00b1L and different subtypes of compensatory cleft speech disorders (i.e., anterior oral CSCs, posterior oral CSCs or non\u2010oral CSCs) measured by perceptual and psychosocial outcome measures. Besides, the experienced acceptability of these three speech intervention approaches were investigated from the perspectives of caregivers and children.<\/jats:p><\/jats:sec><jats:sec><jats:title>What are the potential or actual clinical implications of this work?<\/jats:title><jats:p>This project provides evidence\u2010based knowledge on patient\u2010tailored cleft speech intervention considering both scientific evidence and the perspectives of caregivers and children. The results aid SLPs in better tailoring intervention approaches to the needs of a child with a specific type of compensatory cleft speech disorder.<\/jats:p><\/jats:sec><\/jats:sec>","DOI":"10.1111\/1460-6984.12853","type":"journal-article","created":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T07:36:27Z","timestamp":1675236987000},"page":"1405-1418","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Achieving the next level in cleft speech intervention: A protocol of a randomized sham\u2010controlled trial to provide guidelines for a personalized approach in children with cleft palate"],"prefix":"10.1111","volume":"58","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7593-8595","authenticated-orcid":false,"given":"Cassandra","family":"Alighieri","sequence":"first","affiliation":[{"name":"Department of Rehabilitation Sciences Centre of Speech and Language Sciences Ghent University Gent Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kim","family":"Bettens","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Sciences Centre of Speech and Language Sciences Ghent University Gent Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jamie","family":"Perry","sequence":"additional","affiliation":[{"name":"Department of Communication Sciences and Disorders East Carolina University Greenville NC USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Greet","family":"Hens","sequence":"additional","affiliation":[{"name":"Department Neurosciences KU Leuven Leuven Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nathalie","family":"Roche","sequence":"additional","affiliation":[{"name":"Department of Head and Skin Gent Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kristiane","family":"Van Lierde","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Sciences Centre of Speech and Language Sciences Ghent University Gent Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,1,31]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1037\/0021-9010.69.2.334"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1044\/2020_JSLHR\u201020\u201000129"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/1460\u20106984.12624"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1080\/17549507.2021.1946153"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1044\/2021_JSLHR-21-00405"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/1460-6984.12788"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1597\/15\u2010292"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1201\/9780429258589"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1177\/0022034517723326"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1348\/000712608.377117"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1597\/11\u2010202"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2019.05.018"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2019.01.026"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1177\/1055665619862726"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1597\/1545-1569_1993_030_0064_ppicwc_2.3.co_2"},{"key":"e_1_2_6_17_1","unstructured":"De Bodt M. 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