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This study characterized microbial 16S\n                    <jats:styled-content style=\"fixed-case\">rRNA<\/jats:styled-content>\n                    amplicons and phage metagenomes associated with\n                    <jats:italic>Montastraea annularis<\/jats:italic>\n                    corals during a concurrent white plague disease outbreak and bleaching event. Phage consortia differed between bleached and diseased tissues. Phages in the family\n                    <jats:italic>Inoviridae<\/jats:italic>\n                    were elevated in diseased or healthy tissues compared with bleached portions of diseased tissues. Microbial communities also differed between diseased and bleached corals. Bacteria in the orders\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>R<\/jats:italic>\n                    <\/jats:styled-content>\n                    <jats:italic>hodobacterales<\/jats:italic>\n                    and\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>C<\/jats:italic>\n                    <\/jats:styled-content>\n                    <jats:italic>ampylobacterales<\/jats:italic>\n                    were increased while\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>K<\/jats:italic>\n                    <\/jats:styled-content>\n                    <jats:italic>iloniellales<\/jats:italic>\n                    was decreased in diseased compared with other tissues. A network of phage\u2013bacteria interactions was constructed of all phage strains and 11 bacterial genera that differed across health states. Phage\u2013bacteria interactions varied in specificity: phages interacted with one to eight bacterial hosts while bacteria interacted with up to 59 phages. Six phages were identified that interacted exclusively with\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>R<\/jats:italic>\n                    <\/jats:styled-content>\n                    <jats:italic>hodobacterales<\/jats:italic>\n                    and\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>C<\/jats:italic>\n                    <\/jats:styled-content>\n                    <jats:italic>ampylobacterales<\/jats:italic>\n                    . 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