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Microbiota composition may affect nose inflammatory diseases and\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>S<\/jats:italic>\n                    <\/jats:styled-content>\n                    <jats:italic>taphylococcus aureus<\/jats:italic>\n                    carriage. Considering different nasal cavity locations, microbial colonization was analysed across individuals exhibiting chronic nasal inflammatory diseases (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u200918) and those without local inflammation signs (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u200916). Samples were collected systematically during surgery and examined by an extensive culture\u2010based approach and, for a subset, by 16\n                    <jats:styled-content style=\"fixed-case\">S rRNA<\/jats:styled-content>\n                    gene community profiling. Cultivation yielded 141 taxa with members of\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>S<\/jats:italic>\n                    <\/jats:styled-content>\n                    <jats:italic>taphylococcus<\/jats:italic>\n                    ,\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>C<\/jats:italic>\n                    <\/jats:styled-content>\n                    <jats:italic>orynebacterium<\/jats:italic>\n                    and\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>P<\/jats:italic>\n                    <\/jats:styled-content>\n                    <jats:italic>ropionibacterium<\/jats:italic>\n                    as most common isolates comprising the nasal core culturome together with\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>F<\/jats:italic>\n                    <\/jats:styled-content>\n                    <jats:italic>inegoldia magna<\/jats:italic>\n                    .\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>S<\/jats:italic>\n                    <\/jats:styled-content>\n                    <jats:italic>taphylococcus aureus<\/jats:italic>\n                    was most frequently found in association with\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>S<\/jats:italic>\n                    <\/jats:styled-content>\n                    <jats:italic>taphylococcus epidermidis<\/jats:italic>\n                    and\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>P<\/jats:italic>\n                    <\/jats:styled-content>\n                    <jats:italic>ropionibacterium acnes<\/jats:italic>\n                    , and the posterior vestibules were redefined as\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>S<\/jats:italic>\n                    <\/jats:styled-content>\n                    <jats:italic>. aureus<\/jats:italic>\n                    ' principle habitat. Culturome analysis revealed host\u2010specific bacterial \u2018fingerprints\u2019 irrespective of host\u2010driven factors or intranasal sites. Comparisons between cultivable and molecular fingerprints demonstrated that only a small fraction of phylotypes (6.2%) was correlated. While the total number of different phylotypes was higher in the molecular dataset, the total number of identifications down to the species level was higher in the culturomic approach. To determine host\u2010specific microbiomes, the advantages of molecular approaches should be combined with the resolution and reliability of species identification by culturomic analyses.\n                  <\/jats:p>","DOI":"10.1111\/1462-2920.12891","type":"journal-article","created":{"date-parts":[[2015,4,29]],"date-time":"2015-04-29T01:15:51Z","timestamp":1430270151000},"page":"2130-2142","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":148,"title":["The culturome of the human nose habitats reveals individual bacterial fingerprint patterns"],"prefix":"10.1111","volume":"18","author":[{"given":"Ursula","family":"Kaspar","sequence":"first","affiliation":[{"name":"Institute of Medical Microbiology University Hospital M\u00fcnster  M\u00fcnster Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andr\u00e9","family":"Kriegeskorte","sequence":"additional","affiliation":[{"name":"Institute of Medical 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