{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T23:24:07Z","timestamp":1783121047913,"version":"3.54.6"},"reference-count":68,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2019,10,28]],"date-time":"2019-10-28T00:00:00Z","timestamp":1572220800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31570065"],"award-info":[{"award-number":["31570065"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["enviromicro-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Environmental Microbiology"],"published-print":{"date-parts":[[2019,12]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:p>\n                    <jats:italic>Myxococcus xanthus<\/jats:italic>\n                    kills susceptible bacteria using myxovirescin A (TA) during predation. However, whether prey cells in nature can escape\n                    <jats:italic>M. xanthus<\/jats:italic>\n                    by developing resistance to TA is unknown. We observed that many field\u2010isolated\n                    <jats:italic>Bacillus licheniformis<\/jats:italic>\n                    strains could survive encounters with\n                    <jats:italic>M. xanthus<\/jats:italic>\n                    , which was correlated to their TA resistance. A TA glycoside was identified in the broth of predation\u2010resistant\n                    <jats:italic>B. licheniformis<\/jats:italic>\n                    J32 co\u2010cultured with\n                    <jats:italic>M. xanthus<\/jats:italic>\n                    , and a glycosyltransferase gene (\n                    <jats:italic>yjiC<\/jats:italic>\n                    ) was up\u2010regulated in J32 after the addition of TA. Hetero\u2010expressed YjiC\u2010modified TA to a TA glucoside (TA\u2010Gluc) by conjugating a glucose moiety to the C\u201021 hydroxyl group, and the resulting compound was identical to the TA glycoside present in the co\u2010culture broth. TA\u2010Gluc exhibited diminished bactericidal activity due to its weaker binding with LspA, as suggested by\n                    <jats:italic>in silico<\/jats:italic>\n                    docking data. Heterologous expression of the\n                    <jats:italic>yjiC<\/jats:italic>\n                    gene conferred both TA and\n                    <jats:italic>M. xanthus<\/jats:italic>\n                    \u2010predation resistance to the host\n                    <jats:italic>Escherichia coli<\/jats:italic>\n                    cells. Furthermore, under predatory pressure,\n                    <jats:italic>B. licheniformis<\/jats:italic>\n                    Y071 rapidly developed predation resistance by acquiring TA resistance through the overexpression of\n                    <jats:italic>yjiC<\/jats:italic>\n                    and\n                    <jats:italic>lspA<\/jats:italic>\n                    genes. These results suggest that\n                    <jats:italic>M. xanthus<\/jats:italic>\n                    predation resistance in\n                    <jats:italic>B. licheniformis<\/jats:italic>\n                    is due to the TA deactivation by glucosylation, which is induced in a predator\u2010mediated manner.\n                  <\/jats:p>","DOI":"10.1111\/1462-2920.14817","type":"journal-article","created":{"date-parts":[[2019,10,10]],"date-time":"2019-10-10T19:24:50Z","timestamp":1570735490000},"page":"4755-4772","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":27,"title":["<i>Bacillus licheniformis<\/i>\n                    escapes from\n                    <i>Myxococcus xanthus<\/i>\n                    predation by deactivating myxovirescin A through enzymatic glucosylation"],"prefix":"10.1111","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3535-6712","authenticated-orcid":false,"given":"Chuandong","family":"Wang","sequence":"first","affiliation":[{"name":"State Key Laboratory of Microbial Technology, Microbial Technology Institute Shandong University  Qingdao Shandong 266237 China"},{"name":"School of Life Science Shandong University  Qingdao Shandong 266237 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinlin","family":"Liu","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Microbial Technology, Microbial Technology Institute Shandong University  Qingdao Shandong 266237 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peng","family":"Zhang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Microbial Technology, Microbial Technology Institute Shandong University  Qingdao Shandong 266237 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Wang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Microbial Technology, Microbial Technology Institute Shandong University  Qingdao Shandong 266237 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhifeng","family":"Li","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Microbial Technology, Microbial Technology Institute Shandong University  Qingdao Shandong 266237 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xun","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Medicinal Chemistry, Key Laboratory of Chemistry and Chemical Biology (Ministry of Education), School of Pharmaceutical Science Shandong University  Jinan Shandong 250012 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renqing","family":"Wang","sequence":"additional","affiliation":[{"name":"School of Life Science Shandong University  Qingdao Shandong 266237 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhaohui","family":"Shang","sequence":"additional","affiliation":[{"name":"Gudong Petroleum Production Factory, Shengli Oil\u2010Field of Sinopec  Dongying Shandong 257237 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingen","family":"Yan","sequence":"additional","affiliation":[{"name":"Gudong Petroleum Production Factory, Shengli Oil\u2010Field of Sinopec  Dongying Shandong 257237 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haifeng","family":"He","sequence":"additional","affiliation":[{"name":"Gudong Petroleum Production Factory, Shengli Oil\u2010Field of Sinopec  Dongying Shandong 257237 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Wang","sequence":"additional","affiliation":[{"name":"College of Pharmaceutical Science Shandong University of Traditional Chinese Medicine  Jinan Shandong 250355 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Hu","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Microbial Technology, Microbial Technology Institute Shandong University  Qingdao Shandong 266237 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuezhong","family":"Li","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Microbial Technology, Microbial Technology Institute Shandong University  Qingdao Shandong 266237 China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,10,28]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/femsre\/fuw038"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1017\/S1089332600001133"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2014.00474"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1128\/JB.00559-06"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1128\/JB.00544-07"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-6976.2009.00185.x"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro3380"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjm.2016.10.005"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chembiol.2007.06.008"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-2836(78)90431-X"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/1462-2920.13767"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1038\/ismej.2011.4"},{"key":"e_1_2_6_14_1","volume-title":"Performance Standards for Antimicrobial Suceptibility Testing","author":"CLSI","year":"2016"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1317693111"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1467-7652.2004.00062.x"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-6976.2000.tb00548.x"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.02464-14"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)88911-6"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1099\/mic.0.060343-0"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1021\/acschembio.6b00176"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.7164\/antibiotics.35.1454"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0607335103"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10059-013-0164-0"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.copbio.2014.02.003"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1099\/mic.0.000208"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.3762\/bjoc.12.58"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/1574-6976.12072"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1093\/molbev\/msw054"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-540-46046-6_10"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btm404"},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12257-018-0466-3"},{"key":"e_1_2_6_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/eva.12353"},{"key":"e_1_2_6_34_1","doi-asserted-by":"publisher","DOI":"10.1006\/meth.2001.1262"},{"key":"e_1_2_6_35_1","first-page":"1","article-title":"Transcriptional changes when Myxococcus xanthus preys on Escherichia coli suggest myxobacterial predators are constitutively toxic but regulate their feeding","volume":"4","author":"Livingstone P.G.","year":"2018","journal-title":"Microb Genom"},{"key":"e_1_2_6_36_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2017.01593"},{"key":"e_1_2_6_37_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2017.00439"},{"key":"e_1_2_6_38_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkt1178"},{"key":"e_1_2_6_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2005.01.023"},{"key":"e_1_2_6_40_1","doi-asserted-by":"publisher","DOI":"10.3354\/ame01802"},{"key":"e_1_2_6_41_1","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.00414-10"},{"key":"e_1_2_6_42_1","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.01621-14"},{"key":"e_1_2_6_43_1","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.02448-14"},{"key":"e_1_2_6_44_1","doi-asserted-by":"publisher","DOI":"10.1128\/JB.00575-16"},{"key":"e_1_2_6_45_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2016.00781"},{"key":"e_1_2_6_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.carres.2014.03.011"},{"key":"e_1_2_6_47_1","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.00409-13"},{"key":"e_1_2_6_48_1","doi-asserted-by":"publisher","DOI":"10.14348\/molcells.2014.2348"},{"key":"e_1_2_6_49_1","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.02057-13"},{"key":"e_1_2_6_50_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13568-014-0031-1"},{"key":"e_1_2_6_51_1","doi-asserted-by":"publisher","DOI":"10.1111\/1462-2920.12477"},{"key":"e_1_2_6_52_1","doi-asserted-by":"publisher","DOI":"10.1111\/1462-2920.13171"},{"key":"e_1_2_6_53_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-7915.2010.00208.x"},{"key":"e_1_2_6_54_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pbio.1001547"},{"key":"e_1_2_6_55_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10822-010-9352-6"},{"key":"e_1_2_6_56_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10144-009-0187-8"},{"key":"e_1_2_6_57_1","doi-asserted-by":"publisher","DOI":"10.1002\/cbic.200600075"},{"key":"e_1_2_6_58_1","doi-asserted-by":"publisher","DOI":"10.1002\/jlac.198519850809"},{"key":"e_1_2_6_59_1","doi-asserted-by":"publisher","DOI":"10.1039\/c39820001340"},{"key":"e_1_2_6_60_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.aad3747"},{"key":"e_1_2_6_61_1","doi-asserted-by":"publisher","DOI":"10.1099\/mic.0.065862-0"},{"key":"e_1_2_6_62_1","doi-asserted-by":"publisher","DOI":"10.1039\/c001260m"},{"key":"e_1_2_6_63_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13213-015-1104-3"},{"key":"e_1_2_6_64_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.06148-11"},{"key":"e_1_2_6_65_1","doi-asserted-by":"publisher","DOI":"10.1128\/JB.01361-13"},{"key":"e_1_2_6_66_1","doi-asserted-by":"publisher","DOI":"10.1128\/JB.05052-11"},{"key":"e_1_2_6_67_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10142-013-0333-4"},{"key":"e_1_2_6_68_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-313X.2011.04493.x"},{"key":"e_1_2_6_69_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1523317113"}],"container-title":["Environmental Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2F1462-2920.14817","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1462-2920.14817","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/1462-2920.14817","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/sfamjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1462-2920.14817","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T22:33:45Z","timestamp":1761863625000},"score":1,"resource":{"primary":{"URL":"https:\/\/sfamjournals.onlinelibrary.wiley.com\/doi\/10.1111\/1462-2920.14817"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,10,28]]},"references-count":68,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2019,12]]}},"alternative-id":["10.1111\/1462-2920.14817"],"URL":"https:\/\/doi.org\/10.1111\/1462-2920.14817","archive":["Portico"],"relation":{},"ISSN":["1462-2912","1462-2920"],"issn-type":[{"value":"1462-2912","type":"print"},{"value":"1462-2920","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,10,28]]},"assertion":[{"value":"2019-07-02","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-10-01","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-10-28","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}