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Microbiomes modulate the capacity of insect disease vectors (mosquitoes, tsetse flies, sandflies) to transmit parasites and disease. We investigate the diversity and abundance of microorganisms within the hemolymph (i.e. blood) of\n                    <jats:italic>Biomphalaria<\/jats:italic>\n                    snails, the intermediate host for\n                    <jats:italic>Schistosoma mansoni<\/jats:italic>\n                    , using Illumina MiSeq sequencing of the bacterial 16S V4 rDNA. We sampled hemolymph from five snails from six different laboratory populations of\n                    <jats:italic>B<\/jats:italic>\n                    .\n                    <jats:italic>glabrata<\/jats:italic>\n                    and one population of\n                    <jats:italic>B<\/jats:italic>\n                    .\n                    <jats:italic>alexandrina<\/jats:italic>\n                    . We observed 279.84 \u00b1\u20090.79 amplicon sequence variants per snail. There were significant differences in microbiome composition at the level of individual snails, snail populations and species. Snail microbiomes were dominated by Proteobacteria and Bacteroidetes while water microbiomes from snail tank were dominated by Actinobacteria. We investigated the absolute bacterial load using qPCR: hemolymph samples contained 2784 \u00b1\u2009339 bacteria\/\u03bcl. We speculate that the microbiome may represent a critical, but unexplored intermediary in the snail\u2013schistosome interaction as hemolymph is in very close contact with the parasite at each step of its development.\n                  <\/jats:p>","DOI":"10.1111\/1462-2920.15303","type":"journal-article","created":{"date-parts":[[2020,11,10]],"date-time":"2020-11-10T16:26:40Z","timestamp":1605025600000},"page":"5450-5466","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["The hemolymph of\n                    <i>Biomphalaria<\/i>\n                    snail vectors of schistosomiasis supports a diverse microbiome"],"prefix":"10.1111","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2611-8106","authenticated-orcid":false,"given":"Fr\u00e9d\u00e9ric D.","family":"Chevalier","sequence":"first","affiliation":[{"name":"Texas Biomedical Research Institute  PO Box 760549, San Antonio TX 78258 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robbie","family":"Diaz","sequence":"additional","affiliation":[{"name":"Texas Biomedical Research Institute  PO Box 760549, San Antonio TX 78258 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7821-260X","authenticated-orcid":false,"given":"Marina","family":"McDew\u2010White","sequence":"additional","affiliation":[{"name":"Texas Biomedical Research Institute  PO Box 760549, San Antonio TX 78258 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0191-0204","authenticated-orcid":false,"given":"Timothy J. 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