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Here, we performed a metatransciptomic analysis on three microbial symbionts of the sponge\n                    <jats:italic>Cymbastela concentrica in situ<\/jats:italic>\n                    over 14\u2009months and through differential gene expression and correlation analysis to environmental variables uncovered differences that speak to their metabolic activities and level of symbiotic and environmental interactions. The nitrite\u2010oxidizing\n                    <jats:italic>Ca<\/jats:italic>\n                    . Porinitrospira cymbastela maintained a seemingly stable metabolism, with the few differentially expressed genes related only to stress responses. The heterotrophic\n                    <jats:italic>Ca<\/jats:italic>\n                    . Porivivens multivorans displayed differential use of holobiont\u2010derived compounds and respiration modes, while the ammonium\u2010oxidizing archaeon\n                    <jats:italic>Ca<\/jats:italic>\n                    . Nitrosopumilus cymbastelus differentially expressed genes related to phosphate metabolism and symbiosis effectors. One striking similarity between the symbionts was their similar variation in expression of stress\u2010related genes. Our time\u2010series study showed that the microbial community of\n                    <jats:italic>C. concentrica<\/jats:italic>\n                    undertakes dynamic gene expression adjustments in response to the surroundings, tuned to deal with general stress and metabolic interactions between holobiont members. The success of these dynamic adjustments likely underpins the stability of the sponge holobiont and may provide resilience against environmental change.\n                  <\/jats:p>","DOI":"10.1111\/1462-2920.15962","type":"journal-article","created":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T04:44:14Z","timestamp":1646109854000},"page":"2299-2314","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Communality in microbial stress response and differential metabolic interactions revealed by time\u2010series analysis of sponge symbionts"],"prefix":"10.1111","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5262-1453","authenticated-orcid":false,"given":"Jessica A.","family":"Taylor","sequence":"first","affiliation":[{"name":"Centre for Marine Science and Innovation University of New South Wales  Sydney Australia"},{"name":"School of Biotechnology and Biomolecular Sciences University of New South 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