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One outstanding knowledge gap in understanding Hg methylation is the nature of bioavailable Hg species. It has become increasingly obvious that Hg bioavailability is spatially diverse and temporally dynamic but current models are mostly built on single thiolated ligand systems, omitting ligand exchanges and interactions, or the inclusion of dissolved gaseous phases. In this study, we used a whole\u2010cell anaerobic biosensor to determine the role of a mixture of thiolated ligands on Hg bioavailability. Serendipitously, we discovered how the diffusion of trace amounts of exogenous biogenic H\n                    <jats:sub>2<\/jats:sub>\n                    S, originating from anaerobic microbial ligand degradation, can alter Hg speciation \u2013 away from H\n                    <jats:sub>2<\/jats:sub>\n                    S production site \u2013 to form bioavailable species. Regardless of its origins, H\n                    <jats:sub>2<\/jats:sub>\n                    S stands as a mobile mediator of microbial Hg metabolism, connecting spatially separated microbial communities. At a larger scale, global planetary changes are expected to accelerate the production and mobilization of H\n                    <jats:sub>2<\/jats:sub>\n                    S and Hg, possibly leading to increased production of the potent neurotoxin; this work provides mechanistic insights into the importance of co\u2010managing biogeochemical cycle disruptions.\n                  <\/jats:p>","DOI":"10.1111\/1462-2920.16078","type":"journal-article","created":{"date-parts":[[2022,5,27]],"date-time":"2022-05-27T05:40:18Z","timestamp":1653630018000},"page":"3212-3228","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Diffusion of\n                    <scp>\n                      H\n                      <sub>2<\/sub>\n                      S\n                    <\/scp>\n                    from anaerobic thiolated ligand biodegradation rapidly generates bioavailable mercury"],"prefix":"10.1111","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5060-8407","authenticated-orcid":false,"given":"Benjamin R.","family":"Stenzler","sequence":"first","affiliation":[{"name":"Biology Department University of Ottawa, 30 Marie Curie  Ottawa ON K1N 6N5 Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui","family":"Zhang","sequence":"additional","affiliation":[{"name":"Biology Department University of Ottawa, 30 Marie Curie  Ottawa ON K1N 6N5 Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1670-9984","authenticated-orcid":false,"given":"Jeremy D.","family":"Semrau","sequence":"additional","affiliation":[{"name":"Department of Civil and Environmental Engineering University of Michigan  Ann Arbor MI 48109 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3602-6213","authenticated-orcid":false,"given":"Alan A.","family":"DiSpirito","sequence":"additional","affiliation":[{"name":"Roy J. 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