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The bacterium\n                    <jats:italic>Bacillus cereus<\/jats:italic>\n                    occurs ubiquitously in the environment with certain strain backgrounds causing foodborne and opportunistic infections in humans. The emetic lineage of\n                    <jats:italic>B. cereus<\/jats:italic>\n                    is capable of producing the toxin cereulide, which evokes emetic illnesses. Although food products favouring the accumulation of cereulide are known, the ecological role of cereulide and the environmental niche of emetic\n                    <jats:italic>B. cereus<\/jats:italic>\n                    remain elusive. To better understand the ecology of cereulide\u2010producing\n                    <jats:italic>B. cereus<\/jats:italic>\n                    , we systematically assayed the toxicological spectrum of cereulide on a variety of organisms belonging to different kingdoms. As cereulide is a potassium ionophore, we further tested the effect of environmental potassium levels on the action of cereulide. We found that adverse effects of cereulide exposure are species\u2010specific, which can be exacerbated with increased environmental potassium. Additionally, we demonstrate that cereulide is produced within an insect cadaver indicating its potential ecological function for a saprophytic lifestyle. Collectively, distinct cereulide susceptibilities of other organisms may reflect its role in enabling competitive niche specialization of emetic\n                    <jats:italic>\n                      <jats:sc>B<\/jats:sc>\n                    <\/jats:italic>\n                    .\n                    <jats:italic>cereus<\/jats:italic>\n                    .\n                  <\/jats:p>","DOI":"10.1111\/1462-2920.16454","type":"journal-article","created":{"date-parts":[[2023,6,24]],"date-time":"2023-06-24T21:41:33Z","timestamp":1687642893000},"page":"2231-2249","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["The toxicological spectrum of the\n                    <i>Bacillus cereus<\/i>\n                    toxin cereulide points towards niche\u2010specific specialisation"],"prefix":"10.1111","volume":"25","author":[{"given":"Sabrina","family":"Jenull","sequence":"first","affiliation":[{"name":"Institute of Microbiology, Department of Pathobiology University of Veterinary Medicine Vienna  Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tobias","family":"Bauer","sequence":"additional","affiliation":[{"name":"Institute of Microbiology, Department of Pathobiology University of Veterinary Medicine Vienna  Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katja","family":"Silbermayr","sequence":"additional","affiliation":[{"name":"Institute of Parasitology, Department of Pathobiology University of Veterinary Medicine Vienna  Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maximilian","family":"Dreer","sequence":"additional","affiliation":[{"name":"Department of Functional and Evolutionary Ecology, Archaea Biology and Ecogenomics Unit University of Vienna  Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timo D.","family":"Stark","sequence":"additional","affiliation":[{"name":"Food Chemistry and Molecular Sensory Science Technical University of Munich  Freising Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7384-0594","authenticated-orcid":false,"given":"Monika","family":"Ehling\u2010Schulz","sequence":"additional","affiliation":[{"name":"Institute of Microbiology, Department of Pathobiology University of Veterinary Medicine Vienna  Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,6,24]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-6968.1995.tb07548.x"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-6968.1995.tb07550.x"},{"key":"e_1_2_9_4_1","doi-asserted-by":"crossref","unstructured":"Alonzo D.A.&Schmeing T.M.(2020)Biosynthesis of depsipeptides or Depsi: The peptides with varied generations 29 2316\u20132347. 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