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Here, we report that under limited nutrient availability, the antibacterial activity of\n                    <jats:italic>P. donghuensis<\/jats:italic>\n                    P482 against\n                    <jats:italic>Dickeya solani<\/jats:italic>\n                    requires the reciprocal action of two iron scavengers: 7\u2010hydroxytropolone (7\u2010HT) and a newly characterized pyoverdine (PVD\n                    <jats:sub>P482<\/jats:sub>\n                    ) and is quenched in the iron\u2010augmented environment. Further, we show that the biosynthesis of pyoverdine and 7\u2010HT is metabolically coordinated, and the functional\n                    <jats:italic>BV82_4709<\/jats:italic>\n                    gene involved in 7\u2010HT synthesis is pivotal for expressing the\n                    <jats:italic>BV82_3755<\/jats:italic>\n                    gene, essential for pyoverdine biosynthesis and vice versa. The synthesis of both scavengers is under the control of Gac\/Rsm, but only PVD is controlled by Fur. The isoelectric focusing profile of the P482 siderophore differs from that of the other\n                    <jats:italic>Pseudomonas<\/jats:italic>\n                    spp. tested. This finding led to the unveiling of the chemical structure of the new pyoverdine PVD\n                    <jats:sub>P482<\/jats:sub>\n                    . To summarize, the antibacterial activity of\n                    <jats:italic>P. donghuensis<\/jats:italic>\n                    P482 is attributed to 7\u2010HT and PVD\n                    <jats:sub>P482<\/jats:sub>\n                    varies depending on the nutrient and iron availability, highlighting the importance of these factors in the competition between P482 and\n                    <jats:italic>D. solani<\/jats:italic>\n                    .\n                  <\/jats:p>","DOI":"10.1111\/1462-2920.16559","type":"journal-article","created":{"date-parts":[[2023,12,28]],"date-time":"2023-12-28T00:25:46Z","timestamp":1703723146000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["An iron fist in a velvet glove: The cooperation of a novel pyoverdine from\n                    <i>Pseudomonas donghuensis<\/i>\n                    <scp>P482<\/scp>\n                    with 7\u2010hydroxytropolone is pivotal for its antibacterial activity"],"prefix":"10.1111","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4194-6180","authenticated-orcid":false,"given":"Sylwia","family":"Jafra","sequence":"first","affiliation":[{"name":"Laboratory of Plant Microbiology, Intercollegiate Faculty of Biotechnology of the University of Gdansk and the Medical University of Gdansk University of Gdansk  Gdansk Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magdalena","family":"Jab\u0142o\u0144ska","sequence":"additional","affiliation":[{"name":"Laboratory of Plant Microbiology, Intercollegiate Faculty of Biotechnology of the University of Gdansk and the Medical University of Gdansk University of Gdansk  Gdansk Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomasz","family":"Maci\u0105g","sequence":"additional","affiliation":[{"name":"Laboratory of Plant Microbiology, Intercollegiate Faculty of Biotechnology of the University of Gdansk and the Medical 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