{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T04:25:14Z","timestamp":1793593514132,"version":"4.5.0"},"reference-count":49,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T00:00:00Z","timestamp":1784592000000},"content-version":"vor","delay-in-days":20,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["52470094"],"award-info":[{"award-number":["52470094"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["42277025"],"award-info":[{"award-number":["42277025"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["enviromicro-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Environmental Microbiology"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Quorum quenching (QQ) is an effective biological strategy for mitigating membrane biofouling in membrane bioreactors (MBRs), yet the persistence of QQ bacteria under harsh industrial wastewater conditions remains poorly understood. Here, the induction, resuscitation and functional recovery of the viable but nonculturable (VBNC) state in the efficient QQ bacterium\n                    <jats:italic>Brucella<\/jats:italic>\n                    sp. ZJ1 was investigated under salinity and combined phenol\u2010salinity stress. Combined stress markedly accelerated VBNC formation (36\u2009h vs. 10\u2009days under salinity alone) and caused greater oxidative damage, metabolic suppression, structural deterioration and loss of QQ activity. Salinity\u2010induced VBNC cells recovered following stress removal, whereas phenol\u2010salinity\u2010induced cells required resuscitation\u2010promoting factor (Rpf) for efficient revival. Rpf\u2010mediated resuscitation substantially restored both QQ activity and biofilm inhibition capacity. Transcriptomic analysis revealed that VBNC formation was accompanied by coordinated repression of genes involved in central metabolism, DNA replication and protein biosynthesis, together with activation of osmotic adaptation, membrane transport, quorum sensing and oxidative stress response pathways. These findings demonstrate that the VBNC state is an active adaptive strategy that preserves the potential for functional recovery and provides new insights for improving the antifouling performance of QQ\u2010based MBR systems treating high\u2010strength industrial wastewater.\n                  <\/jats:p>","DOI":"10.1111\/1462-2920.70388","type":"journal-article","created":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T08:42:23Z","timestamp":1784623343000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Salinity and Phenol\u2010Induced\n                    <scp>VBNC<\/scp>\n                    State of Quorum\u2010Quenching Bacterium and Its Resuscitation Strategies for Biofilm Control in Industrial Wastewater Treatment"],"prefix":"10.1111","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0109-848X","authenticated-orcid":false,"given":"Xiaomei","family":"Su","sequence":"first","affiliation":[{"name":"Zhejiang Key Laboratory of Digital Intelligence Monitoring and Restoration of Watershed Environment, College of Geography and Environmental Science Zhejiang Normal University  Jinhua China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qian","family":"Zhang","sequence":"additional","affiliation":[{"name":"Zhejiang Key Laboratory of Digital Intelligence Monitoring and Restoration of Watershed Environment, College of Geography and Environmental Science Zhejiang Normal University  Jinhua China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tianqi","family":"Song","sequence":"additional","affiliation":[{"name":"Zhejiang Key Laboratory of Digital Intelligence Monitoring and Restoration of Watershed Environment, College of Geography and Environmental 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