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However, research has shown that genetic information is interpreted and acted upon through a rich repertoire of adaptable social, cultural and familial factors which pre\u2010exist and interact with biomedical knowledge. This paper reports research into families living with Neurofibromatosis Type 1 (<jats:styled-content style=\"fixed-case\">NF<\/jats:styled-content>1), a highly uncertain condition the manifestation of which can vary considerably also within the same family and, for this reason, has been defined as a \u2018condition without parameters\u2019. These characteristics make<jats:styled-content style=\"fixed-case\">NF<\/jats:styled-content>1 a particularly informative condition for the examination of family dynamics around genetic information. The study and the methodology are based on the exploration of family networks and allow us to investigate the interrelation of individual and familial constructions of the uncertainty of<jats:styled-content style=\"fixed-case\">NF<\/jats:styled-content>1. This also allows both theoretical and policy claims to be made about the danger of reductionist thinking about the transformative potential of genetic technologies.<\/jats:p>","DOI":"10.1111\/1467-9566.12401","type":"journal-article","created":{"date-parts":[[2016,2,12]],"date-time":"2016-02-12T00:00:09Z","timestamp":1455235209000},"page":"753-767","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Families dealing with the uncertainty of genetic disorders: the case of Neurofibromatosis Type 1"],"prefix":"10.1111","volume":"38","author":[{"given":"Daniele","family":"Carrieri","sequence":"first","affiliation":[{"name":"Egenis Department of Sociology, Philosophy and Anthropology University of Exeter UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hannah","family":"Farrimond","sequence":"additional","affiliation":[{"name":"Egenis Department of Sociology, Philosophy and Anthropology University of Exeter UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susan","family":"Kelly","sequence":"additional","affiliation":[{"name":"Egenis Department of Sociology, Philosophy and Anthropology University of Exeter UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Turnpenny","sequence":"additional","affiliation":[{"name":"Clinical Genetics Royal Devon &amp; Exeter Hospital Exeter UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,2,11]]},"reference":[{"key":"e_1_2_9_2_1","volume-title":"Intangibles: the psychologic implications of uncertainty, diagnosis, chronicity and prognosis in NF. 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