{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T22:22:48Z","timestamp":1791325368736,"version":"4.3.1"},"reference-count":14,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2014,7,1]],"date-time":"2014-07-01T00:00:00Z","timestamp":1404172800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,7,1]],"date-time":"2015-07-01T00:00:00Z","timestamp":1435708800000},"content-version":"vor","delay-in-days":365,"URL":"https:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Microbiology and Infection"],"published-print":{"date-parts":[[2014,7]]},"DOI":"10.1111\/1469-0691.12439","type":"journal-article","created":{"date-parts":[[2013,11,1]],"date-time":"2013-11-01T08:58:56Z","timestamp":1383296336000},"page":"O446-O449","source":"Crossref","is-referenced-by-count":23,"title":["Patients with cystic fibrosis have a high carriage rate of non-toxigenic Clostridium difficile"],"prefix":"10.1016","volume":"20","author":[{"given":"M.P.","family":"Bauer","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Farid","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Bakker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.A.S.","family":"Hoek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.J.","family":"Kuijper","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.T.","family":"van Dissel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1111\/1469-0691.12439_bib1","doi-asserted-by":"crossref","first-page":"e1001172","DOI":"10.1371\/journal.pmed.1001172","article-title":"Characterisation of Clostridium difficile hospital ward-based transmission using extensive epidemiological data and molecular typing","volume":"9","author":"Walker","year":"2012","journal-title":"PLoS Med"},{"key":"10.1111\/1469-0691.12439_bib2","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1093\/infdis\/148.1.176","article-title":"Isolation rate and toxigenic potential of Clostridium difficile isolates from patients with cystic fibrosis","volume":"148","author":"Wu","year":"1983","journal-title":"J Infect Dis"},{"key":"10.1111\/1469-0691.12439_bib3","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1136\/jcp.39.9.1013","article-title":"Asymptomatic carriage of Clostridium difficile in patients with cystic fibrosis","volume":"39","author":"Peach","year":"1986","journal-title":"J Clin Pathol"},{"key":"10.1111\/1469-0691.12439_bib4","first-page":"805","article-title":"Clostridium difficile in patients with cystic fibrosis","volume":"139","author":"Welkon","year":"1985","journal-title":"Am J Dis Child"},{"key":"10.1111\/1469-0691.12439_bib5","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.1111\/j.1469-0691.2007.01793.x","article-title":"Characteristics and incidence of Clostridium difficile-associated disease in The Netherlands, 2005","volume":"13","author":"Paltansing","year":"2007","journal-title":"Clin Microbiol Infect"},{"key":"10.1111\/1469-0691.12439_bib6","doi-asserted-by":"crossref","first-page":"2484","DOI":"10.1128\/JCM.38.7.2484-2487.2000","article-title":"Comparison of PCR-ribotyping, arbitrarily primed PCR, and pulsed-field gel electrophoresis for typing Clostridium difficile","volume":"38","author":"Bidet","year":"2000","journal-title":"J Clin Microbiol"},{"key":"10.1111\/1469-0691.12439_bib7","doi-asserted-by":"crossref","first-page":"2178","DOI":"10.1128\/JCM.36.8.2178-2182.1998","article-title":"Identification of toxin A-negative, toxin B-positive Clostridium difficile by PCR","volume":"36","author":"Kato","year":"1998","journal-title":"J Clin Microbiol"},{"key":"10.1111\/1469-0691.12439_bib8","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1111\/j.1574-6968.2000.tb09122.x","article-title":"Production of actin-specific ADP-ribosyltransferase (binary toxin) by strains of Clostridium difficile","volume":"186","author":"Stubbs","year":"2000","journal-title":"FEMS Microbiol Lett"},{"key":"10.1111\/1469-0691.12439_bib9","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1136\/bmj.300.6722.439","article-title":"Detection of pseudodiarrhoea by simple clinical assessment of intestinal transit rate","volume":"300","author":"O'Donnell","year":"1990","journal-title":"BMJ"},{"key":"10.1111\/1469-0691.12439_bib10","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1016\/0895-4356(92)90133-8","article-title":"Adapting a clinical comorbidity index for use with ICD-9-CM administrative databases","volume":"45","author":"Deyo","year":"1992","journal-title":"J Clin Epidemiol"},{"key":"10.1111\/1469-0691.12439_bib11","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1093\/infdis\/147.4.733","article-title":"Antagonism of toxigenic Clostridium difficile by nontoxigenic C. difficile","volume":"147","author":"Wilson","year":"1983","journal-title":"J Infect Dis"},{"key":"10.1111\/1469-0691.12439_bib12","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.anaerobe.2013.05.005","article-title":"A clinical and epidemiological review of non-toxigenic Clostridium difficile","volume":"22","author":"Natarajan","year":"2013","journal-title":"Anaerobe"},{"key":"10.1111\/1469-0691.12439_bib13","doi-asserted-by":"crossref","first-page":"5224","DOI":"10.1128\/AAC.00913-12","article-title":"Evaluation of an oral suspension of VP20621, spores of nontoxigenic Clostridium difficile strain M3, in healthy subjects","volume":"56","author":"Villano","year":"2012","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1111\/1469-0691.12439_bib14","doi-asserted-by":"crossref","first-page":"41","DOI":"10.4161\/gmic.22430","article-title":"Cystic fibrosis transmembrane conductance regulator knockout mice exhibit aberrant gastrointestinal microbiota","volume":"4","author":"Lynch","year":"2013","journal-title":"Gut Microbes"}],"container-title":["Clinical Microbiology and Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1198743X1461171X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1198743X1461171X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,8,7]],"date-time":"2020-08-07T07:02:48Z","timestamp":1596783768000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1198743X1461171X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,7]]},"references-count":14,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2014,7]]}},"alternative-id":["S1198743X1461171X"],"URL":"https:\/\/doi.org\/10.1111\/1469-0691.12439","relation":{},"ISSN":["1198-743X"],"issn-type":[{"value":"1198-743X","type":"print"}],"subject":[],"published":{"date-parts":[[2014,7]]}}}