{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T06:08:54Z","timestamp":1782972534213,"version":"3.54.5"},"reference-count":28,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2013,5,7]],"date-time":"2013-05-07T00:00:00Z","timestamp":1367884800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"National Institute of Digestive Disorders and Kidney Diseases","award":["U01 DK066134 to N.L.P."],"award-info":[{"award-number":["U01 DK066134 to N.L.P."]}]},{"DOI":"10.13039\/501100004359","name":"Swedish Research Council","doi-asserted-by":"crossref","award":["K2010-21574-01-4 to D.A."],"award-info":[{"award-number":["K2010-21574-01-4 to D.A."]}],"id":[{"id":"10.13039\/501100004359","id-type":"DOI","asserted-by":"crossref"}]},{"name":"OAB-LUTS Competitive Grants Program, Pfizer Inc."}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJOG"],"published-print":{"date-parts":[[2013,9]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To investigate the association between a history of gestational diabetes mellitus (<jats:styled-content style=\"fixed-case\">GDM<\/jats:styled-content>) and overactive bladder (<jats:styled-content style=\"fixed-case\">OAB<\/jats:styled-content>) in women of premenopausal age.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>Population\u2010based study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>The Swedish Twin Register.<\/jats:p><\/jats:sec><jats:sec><jats:title>Population<\/jats:title><jats:p>In 2005, a total of 14\u00a0094 female twins born between 1959 and 1985 in the Swedish Twin Registry participated in a comprehensive survey on common exposures and complex diseases. Structured questions provided information on <jats:styled-content style=\"fixed-case\">GDM<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">OAB<\/jats:styled-content>. The present study was designed as a cross\u2010sectional analysis including all women in the cohort having given birth before 2005 (<jats:italic>n<\/jats:italic>\u00a0=\u00a07855).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A logistic regression model based on generalised estimating equations was used to derive odds ratios (ORs).<\/jats:p><\/jats:sec><jats:sec><jats:title>Main outcome measure<\/jats:title><jats:p>The association between a history of <jats:styled-content style=\"fixed-case\">GDM<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">OAB<\/jats:styled-content> was estimated using <jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>s with 95%\u00a0confidence intervals (<jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>s).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The prevalence of <jats:styled-content style=\"fixed-case\">OAB<\/jats:styled-content> in women with a history of <jats:styled-content style=\"fixed-case\">GDM<\/jats:styled-content> was 19.1% compared with 10.7% in women without <jats:styled-content style=\"fixed-case\">GDM<\/jats:styled-content>. This corresponded to a two\u2010fold increased odds of <jats:styled-content style=\"fixed-case\">OAB<\/jats:styled-content> in women with a history of gestational diabetes (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>\u00a02.13, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 1.48\u20133.05). After adjusting the analysis for age, body mass index, parity, smoking, and diabetes mellitus, having had <jats:styled-content style=\"fixed-case\">GDM<\/jats:styled-content> was associated with doubled odds of <jats:styled-content style=\"fixed-case\">OAB<\/jats:styled-content> (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content> 1.88, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 1.26\u20132.80).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>A history of <jats:styled-content style=\"fixed-case\">GDM<\/jats:styled-content> was positively associated with <jats:styled-content style=\"fixed-case\">OAB<\/jats:styled-content> among women of premenopausal age. The association does not seem to be mediated by body mass index or type\u2010I or type\u2010<jats:styled-content style=\"fixed-case\">II<\/jats:styled-content> diabetes mellitus.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1471-0528.12253","type":"journal-article","created":{"date-parts":[[2013,5,7]],"date-time":"2013-05-07T09:23:36Z","timestamp":1367918616000},"page":"1289-1295","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Association between gestational diabetes mellitus and subsequent overactive bladder among premenopausal female twins"],"prefix":"10.1111","volume":"120","author":[{"given":"G","family":"Tettamanti","sequence":"first","affiliation":[{"name":"Division of Obstetrics and Gynaecology Department of Medical Epidemiology and Biostatistics Karolinska Institutet Danderyd Hospital Stockholm 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