{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,8,6]],"date-time":"2024-08-06T07:37:42Z","timestamp":1722929862522},"reference-count":12,"publisher":"Wiley","issue":"13","license":[{"start":{"date-parts":[[2013,9,10]],"date-time":"2013-09-10T00:00:00Z","timestamp":1378771200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJOG"],"published-print":{"date-parts":[[2013,12]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Evidence summaries of tocolytic effectiveness assign quality levels based on a single dimension: the study design. The Grading of Recommendations Assessment, Development and Evaluation (<jats:styled-content style=\"fixed-case\">GRADE<\/jats:styled-content>) system takes into account several domains, including limitations of the study design and ranking the importance of outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>The aim of the study was to compare the quality of evidence according to <jats:styled-content style=\"fixed-case\">GRADE<\/jats:styled-content> with the quality as described by existing guidelines.<\/jats:p><\/jats:sec><jats:sec><jats:title>Search strategy<\/jats:title><jats:p>A practitioner survey to rank the importance of outcomes and a systematic review were conducted. For the systematic review, we searched Medline, Embase, and <jats:styled-content style=\"fixed-case\">DARE<\/jats:styled-content> databases from inception to December 2010 using the terms \u2018tocolytics\u2019 and \u2018threatened preterm labour\u2019, without any language restrictions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Selection criteria<\/jats:title><jats:p>Inclusion criteria for the review were randomised controlled trials comparing tocolytics with either placebo or betamimetics.<\/jats:p><\/jats:sec><jats:sec><jats:title>Data collection and analysis<\/jats:title><jats:p>The review and survey teams worked independently. Evidence ratings according to <jats:styled-content style=\"fixed-case\">GRADE<\/jats:styled-content> were performed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Main results<\/jats:title><jats:p>The majority of the survey respondents thought that it was important to use tocolytics to buy the time needed for steroids to promote fetal lung maturation and to allow <jats:italic>in utero<\/jats:italic> transfer. Nearly 80% of \u2018high\u2019 ratings in guidelines were downgraded as a result of deficiencies identified by <jats:styled-content style=\"fixed-case\">GRADE<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Authors\u2019 conclusions<\/jats:title><jats:p>We propose a move away from the use of evidence rating systems reliant solely on study design, as they have a propensity towards strong recommendations when the underlying evidence is weak.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1471-0528.12388","type":"journal-article","created":{"date-parts":[[2013,9,11]],"date-time":"2013-09-11T09:14:49Z","timestamp":1378890889000},"page":"1588-1598","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["What do we know about tocolytic effectiveness and how do we use this information in guidelines? A comparison of evidence grading"],"prefix":"10.1111","volume":"120","author":[{"given":"C","family":"Roos","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynaecology Radboud University Nijmegen Medical Centre Nijmegen the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E","family":"Borowiack","sequence":"additional","affiliation":[{"name":"Arcana Institute Kracow Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Kowalska","sequence":"additional","affiliation":[{"name":"Arcana Institute Kracow Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Zapalska","sequence":"additional","affiliation":[{"name":"Arcana Institute Kracow Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"BW","family":"Mol","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology Academic Medical Centre Amsterdam the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L","family":"Mignini","sequence":"additional","affiliation":[{"name":"Centre of Perinatal Studies of Rosario Rosario Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C","family":"Meads","sequence":"additional","affiliation":[{"name":"Centre for Health Sciences Barts and The London School of Medicine and Dentistry Queen Mary University of London London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Walczak","sequence":"additional","affiliation":[{"name":"Arcana Institute Kracow Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"KS","family":"Khan","sequence":"additional","affiliation":[{"name":"Centre for Health Sciences Barts and The London School of Medicine and Dentistry Queen Mary University of London London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"the EBM CONNECT collaboration","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,9,10]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(08)60136-1"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.50.4.515"},{"volume-title":"Tocolysis for Women in Preterm Labour","year":"2011","author":"RCOG","key":"e_1_2_9_4_1"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.39489.470347.AD"},{"volume-title":"WHO Handbook for Guideline Development","year":"2010","author":"WHO","key":"e_1_2_9_6_1"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1136\/ebm0005"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0029-7844(03)00395-8"},{"key":"e_1_2_9_9_1","unstructured":"NVOG.Dreigende vroeggeboorte [Threatened preterm labor]. National guidelines Dutch Society of Obstetrics and Gynecology 2004."},{"key":"e_1_2_9_10_1","unstructured":"Preterm Labour Management.South Australia Perinatal Practice Guideline 2011; Chapter 30. Available at:http:\/\/www.health.sa.gov.au\/ppg\/Default.aspx?PageContentMode=1&tabid=70. Accessed 12 July 2013."},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.324.7337.606"},{"key":"e_1_2_9_12_1","first-page":"144","volume-title":"Health Measurement Scales: A Practical Guide to Their Development and Use","author":"Streiner DL","year":"1995"},{"key":"e_1_2_9_13_1","doi-asserted-by":"crossref","unstructured":"WinterG.A comparative discussion of the notion of \u2018validity\u2019 in qualitative and quantitative research. The qualitative report.2000; 4. Available at:http:\/\/www.nova.edu\/ssss\/QR\/QR4-3\/winter.html. Accessed 21 September 2007.","DOI":"10.46743\/2160-3715\/2000.2078"}],"container-title":["BJOG: An International Journal of Obstetrics &amp; Gynaecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2F1471-0528.12388","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1471-0528.12388","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T17:54:35Z","timestamp":1696355675000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1111\/1471-0528.12388"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,9,10]]},"references-count":12,"journal-issue":{"issue":"13","published-print":{"date-parts":[[2013,12]]}},"alternative-id":["10.1111\/1471-0528.12388"],"URL":"https:\/\/doi.org\/10.1111\/1471-0528.12388","archive":["Portico"],"relation":{},"ISSN":["1470-0328","1471-0528"],"issn-type":[{"type":"print","value":"1470-0328"},{"type":"electronic","value":"1471-0528"}],"subject":[],"published":{"date-parts":[[2013,9,10]]},"assertion":[{"value":"2013-02-26","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2013-09-10","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}