{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T00:00:06Z","timestamp":1792627206324,"version":"4.5.0"},"reference-count":19,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2013,10,23]],"date-time":"2013-10-23T00:00:00Z","timestamp":1382486400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJOG"],"published-print":{"date-parts":[[2014,3]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To review our experience with a screening programme that included four sequential cervical length (<jats:styled-content style=\"fixed-case\">CL<\/jats:styled-content>) measurements from 16 to 22<jats:sup>\u00a0<\/jats:sup>weeks of gestation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>Historical cohort study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Tertiary\u2010care centre in a university hospital.<\/jats:p><\/jats:sec><jats:sec><jats:title>Population<\/jats:title><jats:p>There were 312 singleton pregnancies in 321 women with a previous large loop excision of the transformation zone (<jats:styled-content style=\"fixed-case\">LLETZ<\/jats:styled-content>), and 62 pregnancies after a second\u2010trimester miscarriage in a previous pregnancy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The <jats:styled-content style=\"fixed-case\">CL<\/jats:styled-content> measurements were performed by transvaginal ultrasound at 16, 18, 20, and 22 completed weeks of gestation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Main outcome measures<\/jats:title><jats:p>Early preterm delivery before 34 completed weeks of gestation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Early preterm delivery was found in 7.4%. The <jats:styled-content style=\"fixed-case\">CL<\/jats:styled-content> at 16 completed weeks of gestation was smaller in the <jats:styled-content style=\"fixed-case\">LLETZ<\/jats:styled-content> group (36\u00a0mm, interquartile range 30\u201340\u00a0mm) compared with the control group (38\u00a0mm, interquartile range 32\u201342\u00a0mm; <jats:italic>P<\/jats:italic>\u00a0=\u00a00.040). For the analysis of risk factors for early preterm delivery after <jats:styled-content style=\"fixed-case\">LLETZ<\/jats:styled-content>, only cases with a complete data set were included (<jats:italic>n<\/jats:italic>\u00a0=\u00a0145). In a multivariate analysis, two parameters remained significantly predictive, with <jats:styled-content style=\"fixed-case\">CL<\/jats:styled-content> at 16 completed weeks of gestation being the most significant measure (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001, <jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>\u00a00.90, 95%\u00a0<jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 0.83\u20130.98), followed by conception using <jats:styled-content style=\"fixed-case\">IVF<\/jats:styled-content> treatment (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.031, <jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>\u00a00.64, 95%\u00a0<jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 1.54\u201334.80).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Even as early as 16\u00a0weeks of gestation, women with early preterm delivery reveal a significantly lower <jats:styled-content style=\"fixed-case\">CL<\/jats:styled-content> than those without. Dynamics in the <jats:styled-content style=\"fixed-case\">CL<\/jats:styled-content> do not add to this information.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1471-0528.12390","type":"journal-article","created":{"date-parts":[[2013,10,23]],"date-time":"2013-10-23T14:46:04Z","timestamp":1382539564000},"page":"457-463","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":31,"title":["Sequential cervical length screening in pregnancies after loop excision of the transformation zone conisation: a retrospective analysis"],"prefix":"10.1111","volume":"121","author":[{"given":"S","family":"Pils","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynaecology Medical University of Vienna Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W","family":"Eppel","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology Medical University of Vienna Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R","family":"Seemann","sequence":"additional","affiliation":[{"name":"Department of Craniomaxillofacial and Oral Surgery Medical University of Vienna Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C","family":"Natter","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology Medical University of Vienna Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J","family":"Ott","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology Medical University of Vienna Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,10,23]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2011.03252.x"},{"key":"e_1_2_7_3_1","first-page":"4141","article-title":"Large loop excision of the transformation zone and cervical intraepithelial neoplasia: a 22\u2010year experience","volume":"32","author":"Stasinou SM","year":"2012","journal-title":"Anticancer Res"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2303.2009.00669.x"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.a1343"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.a1284"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e3181d068a3"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(06)68181-6"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199602293340904"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.1998.12050312.x"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.2773"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.5333"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2011.03203.x"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2009.02.004"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2012.01.019"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e3181bf1ef2"},{"key":"e_1_2_7_17_1","first-page":"390","article-title":"Prophylactic cerclage in pregnancy. 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